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with aminopyrine N-demethylase as keyword
Gervasi, P.G. Longo, V. Naldi, F. Panattoni, G. Ursino, F.
Published in
Biochemical Pharmacology
Study of oxidative and non-oxidative xenobiotic-metabolizing enzymes was undertaken in microsomal and cytosolic fractions of two human livers, 10 individual and several pooled samples of human respiratory nasal mucosa obtained by surgical operation of male and female patients affected by hypertrophy of the inferior turbinates. The purity of nasal m...
Burke, M.Danny Falzon, Miriam Milton, Anthony S.
Published in
Biochemical Pharmacology
Indomethacin administration to rats caused a dose-dependent decrease in hepatic microsomal cytochrome P450, aminopyrine N-demethylase, ethoxyresorufin O-de-ethylase and benzyloxyresorufin O-debenzylase, accompanied by selective alterations in microsomal sodium dodecylsulphate polyacrylamide gel electrophoretograms. High doses (⪖8.5 mg/kg) caused th...