Periodontitis, a chronic multifactorial inflammatory condition of the periodontium, is originated by a dysbiotic oral microbiota and is negatively correlated with several systemic diseases. The low-chronic burden of gingival inflammation not only exacerbates periodontitis but also predisposes individuals to a spectrum of age-related conditions, inc...
The skin, the largest organ of the human body, plays numerous essential roles, including protection against environmental hazards and the regulation of body temperature. The processes of skin homeostasis and ageing are complex and influenced by many factors, with epigenetic mechanisms being particularly significant. Epigenetics refers to the regula...
Developing Age-Friendly Cities and Communities (AFCCs) is an increasingly popular policy response to supporting ageing populations. AFCC programmes rely on cross-sectoral collaboration, involving partnerships among diverse stakeholders working across sectors to address shared goals. However, there remains a limited understanding of what mechanisms ...
Fixed sleep schedules with an 8 h time in bed (TIB) are used to ensure participants are well-rested before laboratory studies. However, such schedules may lead to cumulative excess wakefulness in young individuals. Effects on older individuals are unknown. We combine modelling and experimental data to quantify the effects of sleep debt on sleep pro...
In this paper, we explore queer temporalities in relation to queer women and non-binary people’s sexuality later in life. Drawing on 30 interviews with 32 queer women and non-binary people aged 49-72 about sexuality and intimacy in later life, we highlight the participants’ stories about the instability and non-linearity of sexuality across the lif...
L'Organisation mondiale de la santé (OMS) OMS recommande une pratique régulière d'activité physique dans la perspective du bien vieillir (OMS). Cette injonction nous conduit à examiner les trajectoires d'activités physiques et sportives des femmes âgées de 60 ans et plus, en mettant l'accent sur les assignations sexuées et les inégalités. L'étude s...
Published in BioEssays : news and reviews in molecular, cellular and developmental biology
A recent thought-provoking theory argues that complex organisms using epigenetic information for their normal development and functioning must irreversibly age as a result of epigenetic signal loss. Importantly, the scope of this theory could be considerably expanded, with scientific benefits, by analyzing epigenetic ageing beyond the borders of th...
Single-time and two-correlators are computed exactly in the 1D Glauber-Ising model after a quench to zero temperature and on a periodic chain of finite length N , using a simple analytical continuation technique. Besides the general confirmation of finitesize scaling in non-equilibrium dynamics, this allows to test the scaling behaviour of the plat...
Published in Frontiers in Neurology
In Periodic Paralysis (PP), a rare inherited condition caused by mutation in skeletal muscle ion channels, the phenotype changes with age, transitioning from the episodic attacks of weakness that give the condition its name, to a more degenerative phenotype of permanent progressive weakness and myopathy. This leads to disability and reduced quality...
Osteoarthritis (OA) is a common chronic condition that causes pain and disability, particularly in the elderly, resulting in significant limitations on mobility and overall quality of life. Balneotherapy using peloids (mud therapy) is an effective, non-pharmacological treatment for OA that improves symptoms and function. This pilot study aimed to a...
