Ultra slow thrombolysis in dysfunctional prosthetic heart valves, a controversial technique in critically ill patients n...
Published in International journal of cardiology. Heart & vasculature
Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotyp...
To evaluate population-based electronic health record (EHR) definitions of atrial fibrillation (AF) and valvular heart disease (VHD) subtypes, time trends in prevalence and prognosis. A total of 76 019 individuals with AF were identified in England in 1998-2010 in the CALIBER resource, linking primary and secondary care EHR. An algorithm was create...
Pressure Volume System for Management of Heart Failure and Valvular Heart Disease
Published in Current Cardiology Reports
Purpose of ReviewTo introduce the reader to the basics of pressure-volume (PV) analysis, its current role in management of heart failure and valvular disease, and the possibilities for future use.Recent FindingsThe recent introduction of FDA-approved miniaturized conductance catheters that can produce PV loops in the clinical setting has set the st...
Pulmonary Hypertension with Valvular Heart Disease: When to Treat the Valve Disease and When to Treat the Pulmonary Hype...
Published in Current Cardiology Reports
Purpose of ReviewThis article will review the current guidelines for therapeutic intervention in (pulmonary hypertension) PH related to left heart disease (PH-LHD).Recent FindingsThe 6th World Symposium on Pulmonary Hypertension (WSPH) recommended that the mean pulmonary artery pressure (mPAP) should be lowered to 20 mmHg. In several randomized con...
Factors Affecting Intermittent Infusion Hemodiafiltration
Published in Blood Purification
Background: Intermittent infusion hemodiafiltration (I-HDF) has been performed for a number of years since this mode of dialysis became available with dialyzers used in Japan. It has been effective in some cases and ineffective in others. In this study, we analyzed and clarified these differences. Summary: We conducted a retrospective study to det...
Hybrid procedure for treating adult congenital heart disease with valvular heart disease in two patients
Published in Journal of Cardiothoracic Surgery
BackgroundThe traditional approach for adult congenital heart disease combined with valvular disease is surgical treatment under cardiopulmonary bypass (CPB). This approach has a high incidence of postoperative complications, especially in patients with pulmonary hypertension and old age. We present two patients in whom the hybrid procedure was use...
Moderate or severe valvular heart disease and outcomes in allogeneic stem cell transplantation.
Published in International journal of cardiology
A Hematopoietic Cell Transplantation-Specific Comorbidity Index (HCT-CI) was previously developed showing that multiple comorbidities including moderate or greater valvular heart disease to be predictors of non-relapse mortality after allogeneic HCT. However, detailed description of the impact of valve disease on outcomes is lacking. Among a large ...
Functional Mitral Valve Regurgitation
Published in Current Cardiovascular Risk Reports
Purpose of ReviewFunctional mitral regurgitation (FMR) occurs when mitral leaflets are prevented from adequate coaptation by underlying left ventricular (LV) dysfunction, mitral annular dilation, or both. This review aims to clarify the complex clinical issues in FMR, including diagnosis and therapy.Recent FindingsEven mild FMR has been shown to af...
Clinical implications of 18F-sodium fluoride uptake in subclinical aortic valve calcification: Its relation to coronary ...
Published in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Uptake of 18F-sodium fluoride (18F-NaF) on positron emission tomography (PET) reflects active calcification. Application of this technique in the early phase of aortic valve calcification (AVC) is of clinical interest. We investigated clinical implications of 18F-NaF uptake in subclinical AVC evaluated simultaneously with coronary atherosclerosis, ...
Management of valvulopathies with acute severe heart failure and cardiogenic shock
Cardiogenic shock is a critical clinical situation, requiring rapid diagnosis, aetiological assessment and immediate initiation of therapy. In industrialized countries, aortic stenosis is the most frequent left-sided valvulopathy, followed by mitral regurgitation, aortic regurgitation and mitral stenosis. Severe valvulopathies leading to cardiogeni...
