Martin, Caitlin Sun, Wei
Published in
Annals of Biomedical Engineering
Transcatheter aortic valve (TAV) implantation within a failed bioprosthetic valve is a growing trend for high-risk patients. The non-compliant stent of the previous prosthesis may prevent full expansion of the TAV, which has been shown to distort the leaflet configuration, and has been hypothesized to adversely affect durability. In this study, TAV...
Stonier, Thomas Harrison, Michael Choong, Andrew M T L
Published in
International journal of cardiology
The available data on TAVI via carotid access demonstrate technical feasibility with comparable outcomes to other traditional access routes. A low number of patients, heterogeneous clinical endpoints and relatively short follow-up periods limit formal meta-analysis and firmer conclusions. For patients in which other access routes are impossible, TA...
Calderan, Joseph Mao, Wenbin Sirois, Eric Sun, Wei
Published in
Artificial organs
Impairment of coronary artery flow, in either acute or chronic conditions, is a severe complication of transcatheter aortic valve (TAV) implantation, which can arise due to improper TAV positioning. However, little work has been done to quantify the effects of the TAV positioning on the coronary flow. In this study, a realistic in vitro model of co...
Wang, Qian
Ph.D.
Wu, Wei Pott, Desiree Mazza, Beniamino Sironi, Tommaso Dordoni, Elena Chiastra, Claudio Petrini, Lorenza Pennati, Giancarlo Dubini, Gabriele Steinseifer, Ulrich
...
Published in
Annals of Biomedical Engineering
Transcatheter aortic valve replacement (TAVR) represents an established recent technology in a high risk patient base. To better understand TAVR performance, a fluid–structure interaction (FSI) model of a self-expandable transcatheter aortic valve was proposed. After an in vitro durability experiment was done to test the valve, the FSI model was bu...
Pascual, Isaac Muñoz-García, Antonio J López-Otero, Diego Avanzas, Pablo Jimenez-Navarro, Manuel F Cid-Alvarez, Belén Del Valle, Raquel Alonso-Briales, Juan H Ocaranza-Sanchez, Raimundo Hernández, José M
...
Published in
Journal of geriatric cardiology : JGC
TAVI is safe and effective in a selected population of very elderly patients. Our findings support the adoption of this new procedure in this complex group of patients.
Wang, Qian Kodali, Susheel Primiano, Charles Sun, Wei
Published in
Biomechanics and Modeling in Mechanobiology
Aortic root rupture is one of the most severe complications of transcatheter aortic valve implantation (TAVI). The mechanism of this adverse event remains mostly unknown. The purpose of this study was to obtain a better understanding of the biomechanical interaction between the tissue and stent for patients with a high risk of aortic rupture. We si...
Gelpi, Guido Romagnoni, Claudia Vismara, Riccardo Antona, Carlo
Published in
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Jilaihawi, Hasan Makkar, Raj R Kashif, Mohammad Okuyama, Kazuaki Chakravarty, Tarun Shiota, Takahiro Friede, Gerald Nakamura, Mamoo Doctor, Niraj Rafique, Asim
...
Published in
European heart journal cardiovascular Imaging
Both leaflet and LVOT calcium are significant predictors of PVL and exert an important synergistic influence on this complication, even in appropriately sized valves. With careful attention to thresholds for detection, clinically relevant leaflet calcium volumes can be identified with either non-contrast or contrast CT scans.
Gunning, Paul S. Vaughan, Ted J. McNamara, Laoise M.
Published in
Annals of Biomedical Engineering
Self expanding Transcatheter Aortic Valve Replacements (TAVR) can conform to the geometry of the aortic annulus and the calcified leaflet complex, which may result in leaflet distortion and altered leaflet kinematics, but such changes have not yet been characterized. In this study we developed a computational model to investigate the deployment of ...
