Hatoum, Hoda Dollery, Jennifer Lilly, Scott M Crestanello, Juan Dasi, Lakshmi Prasad
Published in
The Journal of thoracic and cardiovascular surgery
The goal of this study is to evaluate how sinus flow patterns after transcatheter aortic valve replacement in realistic representative patient roots vary. Sinus flow can affect transcatheter aortic valve operation and likely leaflet thrombosis occurrence due to stasis and poor washout. How the interaction between transcatheter aortic valve and repr...
Rocatello, Giorgia De Santis, Gianluca De Bock, Sander De Beule, Matthieu Segers, Patrick Mortier, Peter
Purpose This study proposes a new framework to optimize the design of a transcatheter aortic valve through patient-specific finite element and fluid dynamics simulation. Methods Two geometrical parameters of the frame, the diameter at ventricular inflow and the height of the first row of cells, were examined using the central composite design. The ...
Vincent, Flavien
Le facteur Willebrand (VWF) est une proteine multimerique qui a une sensibilite unique aux forces de cisaillement et aux variations hemodynamiques du flux sanguin comme celles rencontrees lors d’utilisation de dispositifs cardiovasculaires tels qu’un remplacement valvulaire aortique transcatheter (TAVI) ou un assistance circulatoire mecanique a flu...
Sirois, Eric Mao, Wenbin Li, Kewei Calderan, Joseph Sun, Wei
Published in
Artificial organs
Clinical use of transcatheter aortic valves (TAVs) has been associated with abnormal deployment, including oval deployment and under-expansion when placed into calcified aortic annuli. In this study, we performed an integrated computational and experimental investigation to quantify the impact of abnormal deployment at the aortic annulus on TAV hem...
Hatoum, Hoda Dollery, Jennifer Lilly, Scott M Crestanello, Juan A Dasi, Lakshmi Prasad
Published in
Journal of biomechanics
While in vivo studies clearly demonstrate that supra-annular Valve-in-Valve (ViV) implantation provides the highest probability for optimal post-ViV pressure gradients (PG), there is still no physical insight into explaining anomalies where some supra-annular ViV implantations yield high pressure gradients while some sub-annular implantations yield...
Lee, Nam Ju Jha, Saurabh Lee, Bong Ju Litt, Harold
Published in
Academic radiology
The optimal phase for the measurement of the aortic annular area for transcatheter aortic valve replacement (TAVR) is not standardized, although most agree that systolic measurements are preferred, when the annulus is larger. We hypothesized that the maximum annular area occurs at the cardiac phase of the maximum aortic valve opening (MAVO) and tha...
Börgermann, Jochen Holzhey, David M Thielmann, Matthias Girdauskas, Evaldas Schroefel, Holger Hofmann, Steffen Treede, Hendrik Matschke, Klaus Hilker, Michael Strauch, Justus T
...
Published in
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
The ACURATE TA TM system is a self-expanding transcatheter heart valve system designed for transapical access which has been proven to be safe and effective in the controlled setting of clinical trials. The SAVI-1 and SAVI-2 registries aimed to assess whether these promising outcomes can be translated into all-comers clinical routine. From November...
Dasi, Lakshmi P. Hatoum, Hoda Kheradvar, Arash Zareian, Ramin Alavi, S. Hamed Sun, Wei Martin, Caitlin Pham, Thuy Wang, Qian Midha, Prem A.
...
Published in
Annals of Biomedical Engineering
Transcatheter aortic valves (TAVs) represent the latest advances in prosthetic heart valve technology. TAVs are truly transformational as they bring the benefit of heart valve replacement to patients that would otherwise not be operated on. Nevertheless, like any new device technology, the high expectations are dampened with growing concerns arisin...
Pongratz, Peter Ebbers, Meinolf Geerdes-Fenge, Hilte Reisinger, Emil C
Published in
International journal of surgery case reports
Streptococcus pluranimalium as a novel human pathogen has been reported by several authors in various contexts. In all reported cases in humans the microorganism was detected by the Vitek2®. The great advances with the introduction of new analytical techniques such as MALDI-TOF or 16S rRNA analysis enabled a more detailed discrimination of pathogen...
Armoiry, Xavier Obadia, Jean-Francois Iung, Bernard Polazzi, Stephanie Duclos, Antoine
OBJECTIVES: To describe the clinical outcomes of patients undergoing transcatheter aortic valve implantation (TAVI) and to determine the direct costs before and after TAVI. METHODS: A nationwide longitudinal study using data extracted from the French Hospital Information System. Selection criteria: all patients who underwent TAVI between 1 January ...