Effect of L-tryptophan on diuresis and 5-hydroxyindoleacetic acid excretion in the rat.
Published in British journal of pharmacology and chemotherapy
Oral administration of L-tryptophan to rats produced two main biochemical and pharmacological effects: a marked increase in urinary 5-hydroxyindoleacetic acid excretion, and a significant reduction in the urine flow after a water load. Urinary 5-hydroxyindoleacetic acid excretion reached its maximum 2 to 6 hr after the administration of tryptophan,...