Worboys, Michael Toon, Elizabeth
Published in
History and Philosophy of the Life Sciences
Since the arrival of Translational Medicine (TM), as both a term and movement in the late 1990s, it has been associated almost exclusively with attempts to accelerate the “translation” of research-laboratory findings to improve efficacy and outcomes in clinical practice (Krueger et al. in Hist Philos Life Sci 41:57, 2019). This framing privileges o...
Harrold, Leslie R. Shan, Ying Rebello, Sabrina Kramer, Neil Connolly, Sean E. Alemao, Evo Kelly, Sheila Kremer, Joel M. Rosenstein, Elliot D.
The objective of this study was to compare rheumatoid arthritis (RA) disease activity and patient-reported outcomes (PROs) in a national sample of patients with RA with/without Sjogren's syndrome (SS). Adults with RA from a large observational US registry (Corrona RA) with known SS status between 22 April 2010 and 31 July 2018 and a visit 12 (+/- 3...
Rezk, Mourad F. Pieper, Burkhard
Published in
Advances in Therapy
Immune-mediated inflammatory diseases (IMIDs) are chronic conditions that create a significant disease burden on millions of patients while adding a major financial burden to societies and healthcare systems. The introduction of biologic medicines has contributed majorly to improving the clinical outcomes of IMIDs and as such these modalities have ...
Allenbach, Yves Anquetil, Céline Manouchehri, Ali Benveniste, Olivier Lambotte, Olivier Lebrun-Vignes, Bénédicte Spano, Jean-Philippe Ederhy, Stéphane Klatzmann, David Rosenzwajg, Michelle
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Background: In addition to restoring anti-tumor immune responses, immune checkpoint inhibitors (ICI) may also induce immune-related adverse events (irAE) that can affect any organ. We aim to determine the spectrum, timing, clinical features, and fatalities of rheumatic and musculoskeletal immune-related adverse events (RMS-irAE) associated with ICI...
Alsharief, Alaa N. Laxer, Ronald M. Wang, Qiuyan Stimec, Jennifer Man, Carina Babyn, Paul Doria, Andrea S.
Published in
Insights into Imaging
Purpose1. To review the contemporary literature and present a list of the imaging findings for patients with autoinflammatory diseases from our hospital. All these patients are found to have a genetic mutation that is responsible for their disease.2. To present follow-up imaging findings, when available, and correlate those with symptoms and type o...
Mouyis, Maria
Published in
Advances in Therapy
Caring for women in the postnatal period can be challenging. One of the most important aspects is ensuring disease control as there is a risk of flare in the postpartum period. Other aspects of care also need to be addressed with the mother in mind such as breastfeeding or with the neonate in mind such as vaccinations or complications of the matern...
Santos, C. Sieiro Morales, C. Moriano Álvarez, E. Díez Castro, C. Álvarez Robles, A. López Sandoval, T. Perez
Published in
Clinical Rheumatology
Background Over the month of April, Spain has become the European country with more confirmed cases of COVID-19 infection, after surpassing Italy on April 2nd. The community of Castile and León in Spain is one of the most affected by COVID-19 infection and the province of León has a total of 3711 cases and 425 deaths so far. Rheumatic patients shou...
Nune, A. Iyengar, K. Ahmed, A. Sapkota, H.
Published in
Clinical Rheumatology
COVID-19 has significantly affected healthcare systems around the world. To prepare for this unprecedented emergency, elective patient care was put on hold across the National Health Service (NHS). Rheumatology service had to be reorganised with a cancellation of elective clinics and clinical reconfiguration to continue to deliver care to patients,...
Caporali, Roberto Fakhouri, Walid K. H. Nicolay, Claudia Longley, Harriet J. Losi, Serena Rogai, Veronica
Published in
Advances in Therapy
In the last 20 years, new treatments and a new treatment approach (called treat-to-target) have been introduced for rheumatoid arthritis (RA). Consequently, the characteristics of patients with RA participating in clinical trials of the newest therapies should have changed compared with those of patients who participated in clinical trials of older...
Moon, Jeonghyeon Kim, Dasom Kim, Eun Kyung Lee, Seon-yeong Na, Hyun Sik Kim, Gyoung Nyun Lee, Aram Jung, KyungAh Choi, Jeong Won Park, Sung-Hwan
...
Published in
Scientific Reports
The functions of adipose tissue are associated with autoimmune diseases, such as rheumatoid arthritis (RA). Some studies have shown that the three compositions of adipose tissue (white, brown, and beige) have different functions. Brown adipose tissue (BAT) is known to secrete several factors that differ from those in white adipose tissue. This sugg...
