Plana-Veret, Carlos Seoane-Mato, Daniel Goicoechea García, Carlos Vidal-Fuentes, Javier
Published in
Reumatologia clinica
rheumatic diseases are the most frequent cause of non-malignant chronic pain. In recent years, pain and its management have become more important in rheumatology. to estimate the prevalence and characteristics of pain associated with rheumatic pathology treated in rheumatology clinics in Spain, as well as their treatment and response to it. Multice...
Di Martino, Maria Luisa Frau, Alessandra Losa, Francesca Muggianu, Emma Mura, Mario Nicola Rotta, Gianluca Scotti, Lorenza Marongiu, Francesco
Published in
Scientific Reports
Endothelial damage and fibro-proliferative vasculopathy of small vessels are pathological hallmarks of systemic sclerosis (SSc). The consequence is the detachment of resident elements that become circulating endothelial cells (CECs). The aim of our study was to evaluate the potential of CECs as biomarker in SSc. We enrolled 50 patients with limited...
Banerjee, Arindam Goswami, Rudra Prosad Chatterjee, Moumita
Published in
Scientific Reports
Whenever some phenomenon can be represented as a graph or a network it seems pertinent to explore how much the mathematical properties of that network impact the phenomenon. In this study we explore the same philosophy in the context of immunology. Our objective was to assess the correlation of “size” (number of edges and minimum vertex cover) of t...
Pidde, Giselle Nishiyama, Milton Y. de Oliveira, Ursula Castro Villas-Boas, Isadora M. Paes-Leme, Adriana F. Junqueira-de-Azevedo, Inácio L. Marques-Porto, Rafael Squaiella-Baptistão, Carla C. Tambourgi, Denise V.
Published in
Scientific Reports
The joint disease called pararamosis is an occupational disease caused by accidental contact with bristles of the caterpillar Premolis semirufa. The chronic inflammatory process narrows the joint space and causes alterations in bone structure and cartilage degeneration, leading to joint stiffness. Aiming to determine the bristle components that cou...
Martín-Nares, Eduardo Saavedra-González, Vanessa Fagundo-Sierra, Reynerio Santinelli-Núñez, Blanca Estela Romero-Maceda, Teresa Calderón-Vasquez, Karla Hernandez-Molina, Gabriela
Published in
Scientific Reports
The clinical utility of serum immunoglobulin free light chains (sFLC) in IgG4-related disease (IgG4-RD) is unknown. Herein we evaluated their association with clinical phenotypes, serology and activity in patients with IgG4-RD. Cross-sectional study that included 45 patients with IgG4-RD, and as controls 25 with Sjögren’s syndrome (SS) and 15 with ...
Xu, Haimuzi Kang, Ji-Hyoun Choi, Sung-Eun Park, Dong-Jin Kweon, Sun-Seog Lee, Young-Hoon Kim, Hye-Yeon Lee, Jung-Kil Shin, Min-Ho Lee, Shin-Seok
...
Published in
Scientific Reports
Several studies have evaluated the association between serum adiponectin levels and knee and hand osteoarthritis (OA); mixed results have been reported. We investigated the relationship between OA and serum adiponectin levels according to the radiographic features of knee and hand OA. A total of 2402 subjects was recruited from the Dong-gu Study. B...
Kuo, Pei-I Lin, Tzu-Min Chang, Yu-Sheng Hou, Tsung-Yun Hsu, Hui-Ching Lin, Sheng-Hong Chen, Wei-Sheng Lin, Yi-Chun Wang, Li-Hsuan Chang, Chi-Ching
...
Published in
Scientific Reports
The risk of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in primary Sjogren syndrome (pSS) has rarely been explored. To explore the association between BRONJ and pSS, we conducted a population-based propensity-score-matched cohort study using Taiwan’s National Health Insurance Research Database, including pSS patients receiving antiosteo...
Matsuda, Shogo Kotani, Takuya Suzuka, Takayasu Kiboshi, Takao Fukui, Keisuke Wakama, Minako Ishida, Takaaki Fujiki, Youhei Shiba, Hideyuki Nagai, Koji
...
Published in
Scientific Reports
The prognosis of microscopic polyangiitis (MPA) with interstitial lung disease (ILD) is significantly worse than that of MPA without ILD. However, the clinical characteristics in MPA-ILD, especially poor prognostic factors, are not elucidated. We evaluated demographic, clinical, laboratory, and radiological findings, treatments, and outcomes of 80 ...
Friedman, Benjamin Corciulo, Carmen Castro, Cristina M. Cronstein, Bruce N.
Published in
Scientific Reports
Autophagy, a homeostatic pathway upregulated during cellular stress, is decreased in osteoarthritic chondrocytes and this reduction in autophagy is thought to contribute to the development and progression of osteoarthritis (OA). The adenosine A2A receptor (A2AR) is a potent anti-inflammatory receptor and deficiency of this receptor leads to the dev...
Cavallo, Carola Merli, Giulia Borzì, Rosa Maria Zini, Nicoletta D’Adamo, Stefania Guescini, Michele Grigolo, Brunella Di Martino, Alessandro Santi, Spartaco Filardo, Giuseppe
...
Published in
Scientific Reports
The therapeutic ability of Mesenchymal Stem/Stromal Cells to address osteoarthritis (OA) is mainly related to the secretion of biologically active factors, which can be found within their secreted Extracellular Vesicles including small Extracellular Vesicles (sEV). Aim of this study was to investigate the effects of sEV from adipose derived stromal...