Caravita, Sergio Baratto, Claudia Di Marco, Fabiano Calabrese, Alice Balestrieri, Giulio Russo, Filippo Faini, Andrea Soranna, Davide Perego, Giovanni Battista Badano, Luigi P
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Published in
European journal of heart failure
Interstitial pneumonia due to coronavirus disease 2019 (COVID-19) is often complicated by severe respiratory failure. In addition to reduced lung compliance and ventilation/perfusion mismatch, a blunted hypoxic pulmonary vasoconstriction has been hypothesized, that could explain part of the peculiar pathophysiology of the COVID-19 cardiorespiratory...
Liu, Cong Yang, Lin Cheng, Yuwei Xu, Hongmei Xu, Feng
Published in
BMC Infectious Diseases
Background and purposePertussis is a serious infectious disease in young infants, and severe cases frequently cause death. Our study explored risk factors for death from severe pertussis.MethodA case-control study of infants with severe pertussis admitted to the paediatric intensive care unit (PICU) in the Children’s Hospital of Chongqing Medical U...
Hoyer, Daniel
Published in
Neuropharmacology
Targeting the serotonin (5-HT) system is no simple task: there are at least 15 5-HT receptors, in addition to a number of transporters and metabolizing enzymes. Multiple 5-HT receptor variants exist due to genetic variations and/or post translational modifications, splice variants or editing variants. Some receptors may form homo and heteromers. Th...
Rubio-Rivas, Manuel Homs, Narcís A Cuartero, Daniel Corbella, Xavier
Published in
Autoimmunity reviews
The present study aimed to assess the prevalence and incidence rate of pulmonary arterial hypertension (PAH) in Systemic Sclerosis (SSc). The review was undertaken using MEDLINE and SCOPUS from June 1962 to May 2019 and the terms: ("Scleroderma, Systemic"[MesH]) AND "Hypertension, Pulmonary"[MesH]. The Newcastle-Ottawa Scale (NOS) was used for the ...
Batool, Mehreen Berghausen, Eva M. Zierden, Mario Vantler, Marius Schermuly, Ralph T. Baldus, Stephan Rosenkranz, Stephan ten Freyhaus, Henrik
Published in
Basic Research in Cardiology
Six-transmembrane protein of prostate (Stamp2) protects from diabetes and atherosclerosis in mice via anti-inflammatory mechanisms. As chronic inflammation is a hallmark of pulmonary arterial hypertension (PAH), we investigated the role of Stamp2. Stamp2 expression was substantially reduced in the lung of humans with idiopathic PAH, as well as in e...
Kang, Sok-Leng Contreras, Juan Chaturvedi, Rajiv R
Published in
International journal of cardiology
Creation of a Potts shunt, a connection between the left pulmonary artery (LPA) and descending aorta (DAo), improves functional status and survival in drug-refractory suprasystemic pulmonary arterial hypertension. We investigated a new approach to transcatheter Potts shunt creation in pigs. In six pigs, a steerable SureFlex sheath was used to optim...
Alabed, Samer Garg, Pankaj Johns, Christopher S. Alandejani, Faisal Shahin, Yousef Dwivedi, Krit Zafar, Hamza Wild, James M Kiely, David G Swift, Andrew J
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Published in
Current Cardiovascular Imaging Reports
Purpose of ReviewThis article reviews advances over the past 3 years in cardiac magnetic resonance (CMR) imaging in pulmonary hypertension (PH). We aim to bring the reader up-to-date with CMR applications in diagnosis, prognosis, 4D flow, strain analysis, T1 mapping, machine learning and ongoing research.Recent FindingsCMR volumetric and functional...
Engole, Yannick Mompango Lepira, François Bompeka Nlandu, Yannick Mayamba Lubenga, Yves Simbi Longo, Augustin Luzayadio Nkodila, Aliocha Makulo, Jean-Robert Rissassy Mokoli, Vieux Momeme Bukabau, Justine Busanga Mboliasa, Marie-France Ingole
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Published in
BMC Nephrology
BackgroundAlthough cardiovascular diseases in particular Pulmonary Arterial Hypertension (PAH) is associated with, high morbid-mortality in chronic hemodialysis, but its magnitude remains paradoxically unknown in sub-Saharan Africa. The aim of this study was to evaluate the prevalence of PAH and associated factors in chronic hemodialysis in Sub-Sah...
Wei, Yu Zhao, Cheng Liang, Jun Jin, Ziyi Hua, Bingzhu Wang, Hong Zhang, Huayong Feng, Xuebing
Published in
Clinical rheumatology
To investigate long-term outcomes of Takayasu's arteritis (TA) and explore the predictive factors associated with poor prognosis. We performed a retrospective study on consecutive TA patients admitted to the Nanjing Drum Tower Hospital during the period from July 2010 to March 2019. Potential factors contributing to adverse outcomes, including deat...
Ahmed, Salaheldin Ahmed, Abdulla Bouzina, Habib Lundgren, Jakob Rådegran, Göran
Published in
Heart and vessels
The prevalence of heart failure (HF) is rising with ageing population and constitutes a major health problem globally. A common complication of HF is pulmonary hypertension (PH) which negatively impacts survival. A pathophysiological association between HF and PH with tumorigenic processes has been suggested. We aimed to identify the plasma levels ...
