Iman Islamieh, Davoud PhD Goudarzi, Hossein PhD Khaledi, Azad PhD Afshar, Davoud PhD Esmaeili, Davoud PhD
Published in
Iranian Journal of Medical Sciences
Background: Efflux pumps such as MexEF-OprN and mexXY-OprM play an important role in the resistance of Pseudomonas Aeruginosa ( P. aeruginosa ) to antibiotics. The present study aimed to assess the reduced expression of efflux pump genes of P. aeruginosa with Satureja Khuzistanica essential oil (SKEO). Methods: The present cross-sectional study was...
Gashynova, K. Yu. Suska, K. S. Dmytrychenko, V. V.
Published in
Medicni perspektivi (Medical perspectives)
Chronic respiratory tract infection and relapsing exacerbations worsen the quality and reduce the life expectancy of patients with bronchiectasis. This work aimed to identify the spectrum of pathogens and to determine their profile of antibiotic resistance in the sputum of patients with bronchiectasis in the Dnipro region. Sputum of 60 patients in ...
A. Al-kafaween, Mohammad Mohd Hilmi, Abu Bakar A. Nagi Al-Jamal, Hamid A. Elsahoryi, Nour Jaffar, Norzawani Khairi Zahri, Mohd
Published in
Iranian Journal of Biotechnology
Background: Honey has been known as a traditional medicine for centuries with its antibacterial properties. It is considered one of the most enduring substances used in wound management. Objectives: This study aimed to: (i) evaluate the effects of Malaysian Trigona honey on bacterial structure and (ii) assess the anti-virulence potential of this ho...
Moosavi, Seyed Morteza Pouresmaeil, Omid Zandi, Hengameh Emadi, Sahar Akhavan, Fatemeh Torki, Alireza Astani, Akram
Published in
Reports of Biochemistry & Molecular Biology
Background: Due to extensive damage to the skin, burn victims may acquire life-threatening infections. Though the skin primarily protects against microbial invasions, a large number of bacteria, fungi, and viruses can be isolated from burn patients, specifically Pseudomonas aeruginosa , a gram-negative bacterium with both intrinsic and acquired ant...
Gioia, Bruna
La mucoviscidose (MV) est une maladie génétique rare, causée par la mutation génétique du gène CFTR. Ce gène code un transporteur des ions chlorures, appelé CFTR (Cystic Fibrosis Trans-membrane conductance Regulator) que l’on trouve dans divers organes du corps humain. Cette mutation entraine un défaut du transport ionique. La MV est responsable d’...
Lim, Dong-Jin McCormick, Justin Skinner, Daniel Zhang, Shaoyan Elder, Jeffrey B McLemore, John G Allen, Mark West, John Martin Grayson, Jessica W Rowe, Steven M
...
Published in
International forum of allergy & rhinology
Pseudomonas aeruginosa is common in chronic rhinosinusitus (CRS) and frequently resistant to antibiotic treatment. We recently described the ciprofloxacin and ivacaftor-releasing biodegradable sinus stent (CISS)-a drug-delivery system that administers ciprofloxacin and the mucociliary activator (ivacaftor) at high local concentrations with prolonge...
Khaledi, Azad PhD Meskini, Maryam PhD
Published in
Iranian Journal of Medical Sciences
Background: The use of antibiotics is common, but its excessive or improper use leads to antibiotic resistance. Consequently, scientists have been interested in exploring traditional medicine to identify a new source of anti-bacterial agents. The present study aimed to conduct a systematic review to determine the anti-bacterial activity of Satureja...
Lim, Dong-Jin Skinner, Daniel Mclemore, John Rivers, Nick Elder, Jeffrey Brent Allen, Mark Koch, Connor West, John Zhang, Shaoyan Thompson, Harrison M
...
Published in
International forum of allergy & rhinology
Chronic rhinosinusitis (CRS) is a chronic inflammatory disease characterized by persistent inflammation and bacterial infection. Ciprofloxacin and azithromycin are commonly prescribed antibiotics for CRS, but the ability to provide targeted release in the sinuses could mitigate side effects and improve drug concentrations at the infected site. This...
Bawankar, Pritam Bhattacharjee, Harsha Barman, Manabjyoti Soibam, Ronel Deka, Hemalata Chandra Kuri, Ganesh Medhi, Jnanankar
Published in
Journal of ophthalmic & vision research
To report the investigation of an outbreak of multidrug-resistant (MDR) Pseudomonas aeruginosa endophthalmitis in 13 patients after cataract surgery and to emphasize on the importance of clinical profile, risk factors, and treatment outcomes. This was a hospital-based, retrospective case study with 13 consecutive patients who had man- ual small-inc...
Cho, Do-Yeon Lim, Dong-Jin Mackey, Calvin Weeks, Christopher G Garcia, Jaime A Peña Skinner, Daniel Zhang, Shaoyan McCormick, Justin Woodworth, Bradford A
Published in
International forum of allergy & rhinology
We recently developed a novel ciprofloxacin-coated sinus stent capable of releasing antibiotics over a sustained period of time. Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator that has synergistic bactericidal activity with ciprofloxacin and also enhances sinus mucociliary clearance. The objective of this stud...