Wroclawski, Marcelo Langer Kayano, Paulo Priante Amaral, Breno Santos Mariotti, Guilherme Cayres Yamauchi, Fernando Ide Cha, Jonathan Doyun Carneiro, Arie Korkes, Fernando Vitalli, Alessandra Sousa Mussi, Thais Caldara
...
Published in
Abdominal radiology (New York)
To evaluate the clinical dilemma of men with surgical indication due to benign prostatic enlargement (BPE) and concomitant elevated PSA, we analysed if multiparametric magnetic resonance imaging (mpMRI) could safely prescind the prostate biopsy. Forty men with surgical indication due to BPE and concomitantly elevated PSA levels were prospectively e...
Favorito, Luciano A Pires, Rodrigo S Gallo, Carla M Sampaio, Francisco J B
Published in
Journal of pediatric surgery
To compare the growth of the prostate in anencephalic, prune belly syndrome (PBS) and control fetuses. We studied 35 prostates from normal human fetuses aged 11-22 weeks postconception (WPC); 15 from anencephalic fetuses aged 13-19 WPC; and 6 from PBS fetuses aged 13-31WPC. After prostate dissection, we evaluated the prostate length, width and thic...
Zhang, Chuan Li, Xuhong Boone, Timothy B Cruz, Yolanda Zhang, Yingchun Munoz, Alvaro
Published in
International neurourology journal
This study was conducted to evaluate the hypothesis that an enlarged prostate in old rats may lead to complications associated with voiding dysfunction involving ionotropic P2X2/3-type purinergic receptors. Intact animals were divided into male young (MYR; 8-10 weeks old) and male old (MOR; 20 months old) rats. The animals underwent simultaneous de...
Rudolph, Madhuri Monique Baur, Alexander Daniel Jacques Cash, Hannes Haas, Matthias Mahjoub, Samy Hartenstein, Alexander Hamm, Charlie Alexander Beetz, Nick Lasse Konietschke, Frank Hamm, Bernd
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Published in
Scientific Reports
The purpose of this study is to compare diagnostic performance of Prostate Imaging Reporting and Data System (PI-RADS) version (v) 2.1 and 2.0 for detection of Gleason Score (GS) ≥ 7 prostate cancer on MRI. Three experienced radiologists provided PI-RADS v2.0 scores and at least 12 months later v2.1 scores on lesions in 333 prostate MRI examination...
Ross, M I Bird, N Mendichovszky, I A Rimmer, Y L
BACKGROUND:Brain metastases from prostate cancer are rare and usually only occur in the context of widespread systemic disease. This is the first case report of a solitary brain oligometastasis, in a neurologically intact prostate cancer patient with no other systemic disease, detected using [68Ga]Ga-THP-PSMA PET/CT and only the second one using a ...
Ross, M. I. Bird, N. Mendichovszky, I. A. Rimmer, Y. L.
Published in
EJNMMI Research
BackgroundBrain metastases from prostate cancer are rare and usually only occur in the context of widespread systemic disease. This is the first case report of a solitary brain oligometastasis, in a neurologically intact prostate cancer patient with no other systemic disease, detected using [68Ga]Ga-THP-PSMA PET/CT and only the second one using a P...
Ling, Sheng-Tao Deng, Chun-Lei Huang, Li Yao, Qi-Sheng Liu, Cui Sun, Chuan-Tao Wang, Li Yang, Yong Gong, Xiao-Xin Chen, Cong-Bo
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Published in
Urologia Internationalis
Autophagy is an important pro-survival mechanism and closely related to apoptosis. The aim of this study was to investigate whether hydroxychloroquine (HCQ) blocks autophagy and promotes apoptosis of the prostate after castration. Methods: Thirty-six male SD rats were randomly divided into 3 groups (n = 12): control group (sham operation), castrati...
Zitoun, Osama A Farhat, Abdulrahman Mn Mohamed, Mohamed A Hamad, Mohammad R Aramini, Beatrice Haider, Khawaja Husnain
Published in
European journal of pharmacology
Currently, the main available treatments for benign prostate hyperplasia (BPH) are alpha-1 adrenergic receptor antagonists (ARAs), 5-alpha reductase inhibitors (5-αRI), anticholinergics, and Phosphodiesterase-5 inhibitors. Recent studies support the combined therapy approach using ARAs with 5-αRI for lower urinary tract symptoms (LUTS) in BPH patie...
Panarello, Daniele Compérat, Eva Seyde, Olivia Colau, Alexandre Terrone, Carlo Guillonneau, Bertrand
Published in
European urology focus
Confocal laser endomicroscopy (CLE) is an optical device that aims to image histological architecture and may be used to reduce positive surgical margins. The ability of CLE to describe prostatic and periprostatic tissues, and prostate cancer (PCa) is still an object of investigation. To create an atlas of ex vivo CLE images of prostatic and peripr...
Mota, Paulo Barbosa-Martins, João Moura, Rute S. Lima, Estêvão Miranda, Alice Correia-Pinto, Jorge Carvalho-Dias, Emanuel
Published in
Scientific Reports
Benign prostate hyperplasia is a dysfunctional disease with an elevated prevalence. Despite the accepted impact of aging and testosterone (TES) in its pathophysiology, its aetiology remains unknown. Recent studies described that serotonin (5-HT) inhibits benign prostate growth through the modulation of the androgen receptor, in the presence of TES....
