Franco-Santana, Lucia Estrella Torres-Castillo, Sergio González-Trujano, María Eva González-Ramírez, Misael
Published in
Neurochemistry international
In the present study, the effect of stimulation of the Po-shen and Shen-hun scalp-acupuncture bands on tissue amino acid concentrations in several brain regions in awake and pentobarbital-sedated immature rats was evaluated. Sprague-Dawley rats (aged 15 days) were organized in four groups of at least eight animals: control groups received saline so...
Cheng, Ju-Wen Weber, Alison I Bensmaia, Sliman J
Published in
BMC Anesthesiology
BackgroundWhile pentobarbital has been used extensively in neurophysiological experiments investigating activity in peripheral nerves, it has fallen out of favor as an anesthetic because of safety concerns and is often replaced with isoflurane. However, the effects of isoflurane on the excitability of mechanoreceptive afferents have yet to be concl...
Ghorbani, Ahmad Rakhshandeh, Hassan Sadeghnia, Hamid Reza
Published in
Iranian journal of pharmaceutical research : IJPR
Traditionally, Lactuca sativa (lettuce) has been recommended for its hypnotic property. The present study was planned to investigate sleep-prolonging effect of this plant. The hydro-alcoholic extract (HAE) of lettuce and its water fraction (WF), ethyl acetate fraction (EAF), and n-butanol fraction (NBF) were administrated (IP) to mice 30 min before...
Rašković, Aleksandar Stilinović, Nebojša Mikov, Momir
Published in
BMC Pharmacology and Toxicology
Liu, Zheng Xu, Xin‐Hong Liu, Tian‐Ya Hong, Zong‐Yuan Urade, Yoshihiro Huang, Zhi‐Li Qu, Wei‐Min
Published in
CNS Neuroscience & Therapeutics
Aims: Safranal (2,6,6‐trimethyl‐1,3‐cyclohexadiene‐1‐carboxaldehyde, C10H14O) is an active ingredient in the saffron, which is used in traditional medicine. It has been reported to have sedative and anti‐epileptic effects, but its hypnotic effects remain uncertain. The aim of this study was to evaluate effects of safranal on sleep‐wake cycle. Metho...
Kim, Jae-Wook Kim, Chung-Soo Hu, Zhenzhen Han, Jin-Yi Kim, Si Kwan Yoo, Sung-Kwang Yeo, Yeong Man Chong, Myong Soo Lee, Kinam Hong, Jin Tae
...
Published in
Archives of Pharmacal Research
This experiment was performed to investigate whether apigenin has hypnotic effects and/or enhances pentobarbital-induced sleep behaviors through the GABAergic systems. Apigenin prolonged sleep time induced by pentobarbital similar to muscimol, a GABAA receptors agonist. Apigenin also increased sleep rate and sleep time in the combined administratio...
Ito, Shinichi Sugiyama, Hitomi Kitahara, Seiko Ikemoto, Yoshimi Yokoyama, Takeshi
Published in
Journal of Anesthesia
PurposeNumerous reports suggest that intravenously administered (IV) anesthetics affect postsynaptic events in the central nervous system. However, there is little evidence about how general anesthetics influence the presynaptic processes. The level of presynaptic calcium (Ca2+) concentration ([Ca2+]pre) regulates neurotransmitter release. In this ...
Bischoff, Karyn Jaeger, Robin Ebel, Joseph G.
Published in
Journal of Medical Toxicology
Sodium pentobarbital and phenytoin are common constituents of veterinary euthanasia solutions in the United States. Relay, or secondary, barbiturate toxicosis has been reported in carnivorous animals that have fed from the carcasses of euthanized livestock. This case report presents barbiturate toxicosis in a dog. A 2-year-old female spayed Austral...
Schreiber, John M. Gaillard, William D.
Published in
Current Neurology and Neuroscience Reports
Refractory status epilepticus (RSE) is characterized by a prolonged seizure that persists despite adequate initial management. RSE accounts for almost one quarter of all status epilepticus and carries significant risk for morbidity and mortality. Treatment varies widely between institutions regarding medication choice, dose, and monitoring. Several...
Kuschnereit, R Lehmann, C Whynot, S Hung, O Shukla, R Henzler, D Cerny, V Pavlovic, D Kelly, M
Published in
Critical Care
