The ability to prepare a task is crucial for the voluntary control of our actions. It enables us to react flexibly and rapidly to a changing environment. In the present event-related functional magnetic resonance imaging study we investigated task preparation with a task-cueing paradigm. In this paradigm we intermixed trials in which a task cue and...
Objective: To investigate the current state of knowledge regarding the neurobiology of suicide and suicidality. Method: The literature on the neurobiology of suicidality and suicide was reviewed. Results: There is clear evidence that the activity of 3 neurobiological systems has a role in the pathophysiology of suicidal behaviour. This includes hyp...
It is widely acknowledged that the prefrontal cortex plays a major role in cognitive control processes. One important experimental paradigm for investigating such higher order cognitive control is the task-switching paradigm. This paradigm investigates the ability to switch flexibly between different task situations. In this context, it has been fo...
Published in Human brain mapping
There is growing evidence that a specific region in the posterior frontolateral cortex is involved intimately in cognitive control processes. This region, located in the vicinity of the junction of the inferior frontal sulcus and the inferior precentral sulcus, was termed the inferior frontal junction (IFJ). The IFJ was shown to be involved in the ...
