Introduction Dietary exposure monitoring within populations is reliant on self-reported measures such as Food Frequency Questionnaires and diet diaries. These methods often contain inaccurate information due to participant misreporting, non-compliance and bias. Urinary metabolites derived from individual foods could provide additional objective ind...
Objective: MicroRNA-mediated (dys)regulation of gene expression has been implicated in Parkinson's disease (PD), although results of microRNA expression studies remain inconclusive. We aimed to identify microRNAs that show consistent differential expression across all published expression studies in PD. Mathods: We performed a systematic literature...
Thermal non-equilibrium (TNE) is believed to be a potentially important process in understanding some properties of the magnetically closed solar corona. Through one-dimensional hydrodynamic models, this paper addresses the importance of the numerical spatial resolution, footpoint heating timescales and background heating on TNE. Inadequate transit...
Purpose: Up to 30% of patients with breast cancer relapse after primary treatment. There are no sensitive and reliable tests to monitor these patients and detect distant metastases before overt recurrence. Here, we demonstrate the use of personalized circulating tumor DNA (ctDNA) profiling for detection of recurrence in breast cancer. Experimental ...
We describe the use of a genetic algorithm to apply active feedback to a laser wakefield accelerator at a higher power (10 TW) and a lower repetition rate (5 Hz) than previous work. The temporal shape of the drive laser pulse was adjusted automatically to optimize the properties of the electron beam. By changing the software configuration, differen...
Published in Toxins
A reliable and practical multi-method was developed for the quantification of mycotoxins in plasma, urine, and feces of pigs, and plasma and excreta of broiler chickens using liquid chromatography–tandem mass spectrometry. The targeted mycotoxins belong to the regulated groups, i.e., aflatoxins, ochratoxin A and Fusarium mycotoxins, and to two grou...
Published in Scientific Reports
Several microRNAs (miRNAs) have been linked to chronic kidney disease (CKD) mortality, cardiovascular (CV) complications and kidney disease progression. However, their association with clinical outcomes remains poorly evaluated. We used real-time qPCR to measure serum levels of miR-126 and miR-223 in a large cohort of 601 CKD patients (CKD stage G1...
Context. Collisions between cometary neutrals in the inner coma of a comet and cometary ions that have been picked up into the solar wind flow and return to the coma lead to the formation of a broad inner boundary known as a collisionopause. This boundary is produced by a combination of charge transfer and chemical reactions, both of which are impo...
Solar wind charge-changing reactions are of paramount importance to the physico-chemistry of the atmosphere of a comet. The ESA/Rosetta mission to comet 67P/Churyumov-Gerasimenko (67P) provides a unique opportunity to study charge-changing processes in situ. To understand the role of these reactions in the evolution of the solar wind plasma, and in...
status: published
