Huh, Youn Cho, Hong-Jun
Published in
International journal of environmental research and public health
The relationships between multiple tobacco products, such as heated tobacco products (HTPs), electronic cigarettes (ECs), and combustible cigarettes (CCs), and suicide-related behaviors among adolescents have not been extensively researched. This study examined the associations between the type of tobacco products used and suicidal thoughts, plans,...
van Cann, Marianne; Kuzmenkov, Alexey; Isensee, Jorg; Andreev-Andrievskiy, Alexander; Peigneur, Steve; 56122; Khusainov, Georgii; Berkut, Antonina; Tytgat, Jan; 18354; Vassilevski, Alexander; Hucho, Tim;
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Venoms are a rich source of highly specific toxins, which allow the identification of novel therapeutic targets. We have now applied high content screening (HCS) microscopy to identify toxins that modulate pain sensitization signaling in primary sensory neurons of rat and elucidated the underlying mechanism. A set of venoms and fractions thereof we...
Seefried, Lothar Dahir, Kathryn Petryk, Anna Högler, Wolfgang Linglart, Agnès Martos-Moreno, Gabriel Ángel Ozono, Keiichi Fang, Shona Rockman-Greenberg, Cheryl Kishnani, Priya S
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Published in
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Hypophosphatasia (HPP) is a rare, inherited, metabolic disease caused by deficient tissue non-specific alkaline phosphatase activity. This study aims to assess patient-reported pain, disability and health-related quality of life (HRQoL) in a real-world cohort of adults with HPP who were not receiving asfotase alfa during the analysis. Adults (≥18 y...
Van de Velde, Fréderic E G Ortega-Castrillon, Alejandra Thierens, Laurent A M Claes, Peter De Pauw, Guy A M
Published in
Oral surgery, oral medicine, oral pathology and oral radiology
The aim of this study was to investigate the effect of manual lymphatic drainage (MLD) on postoperative facial swelling and pain. A randomized, single-center, prospective, 2-arm clinical trial with blinded endpoint assessment was set up. Patients were enrolled from the Maxillofacial Department of the Ghent University Hospital (Belgium) between Janu...
Lemoine, A; van de Velde, M; 34202; Jacobs, A; Joshi, G; Bonnet, F;
status: published
Van Wilder, Lisa Clays, Els Devleesschauwer, Brecht Pype, Peter Boeckxstaens, Pauline Schrans, Diego De Smedt, Delphine
Published in
BMJ Open
Introduction Non-communicable diseases (NCDs) are associated with lower health-related quality of life (HRQoL). However, knowledge about those diseases and predictors with a greater impact on patients’ HRQoL as well as knowledge on the complex relationship between HRQoL and comorbidities is lacking. The aim of this study is to assess the impact of ...
Muilu, Paula Rantalaiho, Vappu Kautiainen, Hannu Virta, Lauri Juhani Puolakka, Kari
Published in
The Journal of rheumatology
To assess to what extent the worldwide opioid epidemic affects Finnish patients with early inflammatory arthritis (IA). From the nationwide register maintained by the Social Insurance Institution of Finland, we collected all incident adult patients with newly onset seropositive and seronegative rheumatoid arthritis (RA+ and RA-) and undifferentiate...
Miranda, Rose van der Steen, Jenny T Smets, Tinne Van den Noortgate, Nele Deliens, Luc Payne, Sheila Kylänen, Marika Szczerbińska, Katarzyna Gambassi, Giovanni Van den Block, Lieve
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Published in
International journal of geriatric psychiatry
We aimed to investigate the occurrence rates of clinical events and their associations with comfort in dying nursing home residents with and without dementia. Epidemiological after-death survey was performed in nationwide representative samples of 322 nursing homes in Belgium, Finland, Italy, the Netherlands, Poland, and England. Nursing staff repo...
Coppens, Steve; Rex, Steffen; 77044; Fieuws, Steffen; Neyrinck, Arne; 46197; D'Hoore, Andre; 58479; Dewinter, Geertrui; 58357;
BACKGROUND: Thoracic epidural anesthesia is no longer considered the gold standard for perioperative analgesia in laparoscopic colorectal procedures. In the search for alternatives, the efficacy of the transverse abdominal plane (TAP) block and other abdominal wall blocks such as the transmuscular quadratus lumborum (TQL) block continues to be inve...
Vangeel, Laura; 92149; Benoit, Melissa; Miron, Yannick; Miller, Paul E; De Clercq, Katrien; 92156; Chaltin, Patrick; 14463; Verfaillie, Catherine; 48658; Vriens, Joris; 35360; Voets, Thomas; 6490;
BACKGROUND AND PURPOSE: The transient receptor potential (TRP) ion channel TRPM3 functions as a noxious heat sensor, plays a key role in acute pain sensation and inflammatory hyperalgesia in rodents. Despite its potential as a novel analgesic drug target, little is known about the expression, function and modulation in the humans. EXPERIMENTAL APPR...
