Published in Supportive Care in Cancer
In recent years, significant improvements have been made in the management of neutropenia and thrombocytopenia and other potentially life-threatening complications of ablative chemotherapy. While these complications are of particular concern to physicians, patients receiving ablative therapy for bone marrow or blood stem cell transplants are often ...
Background. Oral mucositis is a common complication of some malignancies treatment, causing therapeutic modifications due to patient's debilitation, which often interferes with the prognosis of the disease. Many attempts have been made to find an optimal treatment or preventive method to minimize the severity of oral mucositis. Several studies have...
Published in Supportive Care in Cancer
BackgroundThe Oral Care Study Section of the Multinational Association of Supportive Care in Cancer (MASCC) and the International Society for Oral Oncology (ISOO) conducted a survey on clinical practices of oral/dental management of cancer patients among supportive health care providers. The main purpose was to evaluate the knowledge and current pr...
Published in Supportive Care in Cancer
Antimicrobial solutions are widely used in the nursing care of chemotherapy induced oral mucositis (OM). There is little evidence, however, supporting their use for reducing mucosal damage. In our study, 132 patients were randomized to use normal saline (n=65) or povidone-iodine diluted 1:100 (n=67) mouthwashes for OM prophylaxis and treatment afte...
Published in Der Hautarzt
Hautveränderungen bei Patienten mit Tumorerkrankungen können viele Ursachen haben und sind nicht leicht einzuteilen. Chemotherapieassoziierte kutane Nebenwirkungen sind meist toxischer Genese und zeigen oft charakteristische Reaktionsmuster, die sich dem dermatologisch geschulten Auge erschließen. Schwerwiegende chemotherapieassoziierte Reaktionen ...
Published in Supportive Care in Cancer
Goal of workThe aim of the study is to evaluate the effect of fluconazole antifungal prophylaxis on the severity of mucositis in head and neck cancer patients receiving radiotherapy.Patients and methodsSixty-three patients, with malignant head and neck tumor, eligible to receive radiotherapy, entered the study. Thirty-four patients (group A) receiv...
Published in Supportive Care in Cancer
Goal of workThe aim of the study was to investigate the incidence of herpes simplex virus-1 (HSV-1) infection in mucositis during head and neck cancer radiotherapy.Patients and methodsSixty patients with malignant head and neck tumor, eligible to receive radiotherapy, who were referred to the Dental Oncology Unit, entered the study. Sixteen patient...
Published in Supportive Care in Cancer
Study on the normal saline vs povidone–iodine mouthwashes for oral mucositis (OM) prophylaxis in patients after high-dose chemotherapy comprising bischloroethyl nitrosourea etoposide ara-C melphalan (BEAM) or high-dose melphalan (HD-L-PAM) followed by autologous peripheral stem cell transplantation indicated that females have higher a incidence of ...
Published in Cancer Chemotherapy and Pharmacology
IntroductionMucositis induced by antineoplastic drugs is an important, dose-limiting, and costly side effect of cancer therapy. Aim: To investigate the role of nitric oxide (NO) on the pathogenesis of 5-fluorouracil (5-FU)-induced oral mucositis.Materials and MethodsOral mucositis was induced by two intraperitoneal (i.p) administrations of 5-FU on ...
Published in Supportive Care in Cancer
Goal of the workOral mucositis (OM) is a functionally destructive complication of aggressive head and neck cancer therapy, often resulting in intense pain, an inability to eat and drink and secondary malnutrition and dehydration. The barrier-forming properties of Gelclair have shown promise in relieving such symptoms. The aim of this randomised-con...
