Ramos-Pinto, Mariana Bitu de Lima Gusmão, Teresa Paula Schmidt-Filho, Jayr Jaguar, Graziella Chagas Martins, Manoela Domingues Alves, Fábio Abreu
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
To compare the efficacy of intraoral and extraoral photobiomodulation (PBM) protocols for the prevention of oral mucositis (OM) in hematopoietic stem cell transplantation (HSCT) patients. A total of 60 patients was randomized into intraoral PBM (IOPBM) and extraoral PBM (EOPBM) groups. Both PBM protocols were well tolerated and no side effects were...
Curra, Marina Gabriel, Amanda F Ferreira, Maria Beatriz C Martins, Marco Antonio T Brunetto, André T Gregianin, Lauro J Martins, Manoela Domingues
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
To investigate the incidence and risk factors for oral mucositis (OM) in patients with childhood cancer undergoing chemotherapy. Eight hundred and twenty-nine cycles of chemotherapy were evaluated in 112 patients with childhood cancer undergoing chemotherapy. Chemotherapy protocol, hematological, hepatic, and renal function parameters were collecte...
Kauark-Fontes, Elisa Migliorati, Cesar Augusto Epstein, Joel B. Treister, Nathaniel Simon Alves, Carolina Guimarães Bonfim Faria, Karina Morais Palmier, Natalia Rangel Rodrigues-Oliveira, Leticia de Pauli Paglioni, Mariana Gueiros, Luiz Alcino Monteiro
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Published in
Supportive Care in Cancer
Purpose To assess the safety and efficacy of prophylactic extraoral photobiomodulation (PBM) for the prevention of oral and oropharyngeal mucositis (OM) on clinical outcomes and survival in patients with oral cavity and oropharyngeal squamous cell carcinoma (OOPSCC). Methods OOPSCC patients who received radiotherapy (RT) were prospectively randomiz...
Soutome, Sakiko Yanamoto, Souichi Nishii, Mika Kojima, Yuka Hasegawa, Takumi Funahara, Madoka Akashi, Masaya Saito, Toshiyuki Umeda, Masahiro
Published in
Journal of dental sciences
Radiotherapy for head and neck cancer often causes severe oral mucositis. The purpose of this retrospective study was to further examine the risk factors for developing severe oral mucositis in patients with oral cancer undergoing radiotherapy as a compliment to a previous study performed by our group. A total of 181 patients with oral cancer under...
Nicolatou-Galitis, Ourania Bossi, Paolo Orlandi, Ester René-Jean Bensadoun,
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
To discuss the role of benzydamine in the prevention and treatment of radiation-induced oral mucositis (OM) in head and neck (H&N) cancer patients. This document represents an expert opinion paper on indications and key-role aspects in OM pathogenesis, prevention and treatment. OM represents a common side effect of chemotherapy (CHT) and radiothera...
Bensadoun, René-Jean Bollet, Marc A. Liem, Xavier Cao, Kim Magné, Nicolas
Published in
Supportive Care in Cancer
Purpose The study aims to assess the feasibility, safety, and tolerability of CareMin650, a new photobiomodulation device, in patients treated by radiotherapy (RT) and to collect preliminary data on efficacy for prevention and treatment of oral mucositis (OM) and radiation dermatitis (RD). Methods Safe PBM is a French, multicentric, prospective, no...
Kia, Seyed Javad Basirat, Maryam Saedi, Hamid Saeidi Arab, Seyed Ali
Published in
BMC Complementary Medicine and Therapies
BackgroundOne of the most prevalent complications of chemotherapy and radiotherapy is oral mucositis (OM) and manifests as erythema and ulceration. Curcumin is one of the components of turmeric and possesses anti-inflammatory and anti-oxidative features. Some of studies have proved the effectiveness of Curcumin in OM. This study aimed to investigat...
Palasi, Stephen Zhang, Ning Bankston, Mikaela Godby, Joy Burrows, Hannah Lagunas, Jennifer Perkison, William Gunn, Brandon Chambers, Mark S Rosenthal, David I
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Published in
Clinical and translational radiation oncology
The objective was to identify clinical and epidemiological factors associated with utilization of a complex oral treatment device (COTD), which may decrease toxicity in patients undergoing radiation therapy for head and neck cancer (HNC). We retrospectively reviewed data from 1992 to 2013 in the Surveillance, Epidemiology, and End Results (SEER)-Me...
Nagaoka, Hiroka Momo, Kenji Hamano, Jun Miyaji, Tempei Oyamada, Shunsuke Kawaguchi, Takashi Homma, Masato Yamaguchi, Takuhiro Morita, Tatsuya Kizawa, Yosiyuki
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Published in
Journal of pain and symptom management
Oral mucositis (OM) pain due to anticancer chemo- and radiotherapy has a very negative impact on patient quality of life. However, no high-quality studies have been performed regarding the analgesic efficacy of indomethacin (IM) oral spray for OM pain. This randomized, placebo-controlled, double-blind trial aimed to evaluate the analgesic efficacy ...
Lozano, A Marruecos, J Rubió, J Farré, N Gómez-Millán, J Morera, R Planas, I Lanzuela, M Vázquez-Masedo, M G Cascallar, L
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Published in
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
The objective of this trial was to evaluate the safety and efficacy of melatonin oral gel mouthwashes in the prevention and treatment of oral mucositis (OM) in patients treated with concurrent radiation and systemic treatment for head and neck cancer. Randomized, phase II, double-blind, placebo-controlled trial (1:1 ratio) of 3% melatonin oral gel ...