Wasserman, Richard L Hague, Angela R Pence, Deanna M Sugerman, Robert W Silvers, Stacy K Rolen, Joanna G Herbert, Morley
Published in
The journal of allergy and clinical immunology. In practice
Peanut allergy (PA) is a significant and increasing problem, interfering with psychological development and family life. The standard recommendation to avoid peanut products and have access to injectable epinephrine is often inadequate. Oral immunotherapy for PA has been formally studied. Clinical observations of allergen immunotherapy have repeate...
Epstein-Rigbi, Na'ama Goldberg, Michael R Levy, Michael B Nachshon, Liat Elizur, Arnon
Published in
The journal of allergy and clinical immunology. In practice
Oral immunotherapy (OIT) for food allergy is demanding but data on patients' quality of life (QOL) throughout the process are limited. To characterize changes in QOL of food-allergic patients during and after OIT. In a prospective cohort study, the Food Allergy Quality of Life Questionnaire-Parental Form (FAQLQ-PF) was administered to parents of 19...
Yee, Christina S K Albuhairi, Sultan Noh, Elizabeth El-Khoury, Kristel Rezaei, Shervin Abdel-Gadir, Azza Umetsu, Dale T Burke-Roberts, Elizabeth LeBovidge, Jennifer Schneider, Lynda
...
Published in
The journal of allergy and clinical immunology. In practice
We successfully used omalizumab to facilitate peanut oral immunotherapy (OIT) in children with reactivity to ≤50mg peanut protein and with high peanut IgE (median, 229 kU/L). We report on long-term OIT outcomes in these patients, including dosing changes, adverse events, peanut immunoglobulin changes, and quality of life (QoL). Patients were follow...
Howe, Lauren C Leibowitz, Kari A Perry, Margaret A Bitler, Julie M Block, Whitney Kaptchuk, Ted J Nadeau, Kari C Crum, Alia J
Published in
The journal of allergy and clinical immunology. In practice
Oral immunotherapy (OIT) can lead to desensitization to food allergens, but patients can experience treatment-related symptoms of allergic reactions that cause anxiety and treatment dropout. Interventions to improve OIT for patients are needed. To determine whether fostering the mindset that non-life-threatening symptoms during OIT can signal desen...
Andorf, Sandra Purington, Natasha Kumar, Divya Long, Andrew O'Laughlin, Katherine L Sicherer, Scott Sampson, Hugh Cianferoni, Antonella Whitehorn, Terri Brown Petroni, Daniel
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Published in
EClinicalMedicine
As there is limited data on the sustainability of desensitization of multifood-oral immunotherapy (multifood-OIT), we conducted a multisite multifood-OIT study to compare the efficacy of successful desensitization with sustained dosing vs discontinued dosing after multifood-OIT. We enrolled 70 participants, aged 5-22 years with multiple food allerg...
Evrard, Bertrand Bonnet, B. Jubelin, Grégory Bernalier-Donadille, Annick
Part of special issue:14ème Congrès Francophone d’Allergologie - 16-19 avril 2019 - Paris, Palais des Congrès
De Schryver, Sarah Mazer, Bruce Clarke, Ann E St Pierre, Yvan Lejtenyi, Duncan Langlois, Alexandra Torabi, Bahar Zhao, Wei W Chan, Edmond S Baerg, Ingrid
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Published in
The journal of allergy and clinical immunology. In practice
This study focuses on the side effects of cow's milk oral immunotherapy (CM-OIT) using consensus definitions of food-induced anaphylaxis. To evaluate the risk of allergic reactions (ARs) and to identify risk factors associated with higher risk of anaphylactic ARs (AARs) during CM-OIT in children. Clinical charts of children receiving CM-OIT were ca...
Soller, Lianne Abrams, Elissa M Carr, Stuart Kapur, Sandeep Rex, Gregory A Leo, Sara Lidman, Per G Yeung, Joanne Vander Leek, Timothy K McHenry, Mary
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Published in
The journal of allergy and clinical immunology. In practice
In 2017, a clinical trial of 37 subjects demonstrated that preschool peanut oral immunotherapy (P-OIT) was safe, with predominantly mild symptoms reported and only 1 moderate reaction requiring epinephrine. We sought to examine whether these findings would be applicable in a real-world setting. As part of a Canada-wide quality improvement project, ...
Nachshon, Liat Goldberg, Michael R Levy, Michael B Appel, Michael Y Epstein-Rigbi, Naama Lidholm, Jonas Holmqvist, Marie Katz, Yitzhak Elizur, Arnon
Published in
The journal of allergy and clinical immunology. In practice
The presence of sesame in Western diet is increasing, making its avoidance by sesame-allergic patients more challenging. To report the efficacy and safety of sesame oral immunotherapy (OIT). Sixty patients aged 4 years or older, diagnosed as sesame-allergic on the basis of a positive oral food challenge, were consecutively enrolled into OIT between...
Zhong, Youjia Chew, Jian-Ming Lamony Tan, Michelle Meiling Soh, Jian Yi
Published in
Asia Pacific Allergy
Background Peanut allergy is an increasing problem in Singapore and strict avoidance is difficult as peanut is ubiquitous in Asian cuisine. Objective We aimed to assess the efficacy and safety of peanut oral immunotherapy (OIT) in children with obvious peanut allergy in Singapore. Methods This was an open-label study of peanut OIT in children livin...
