Published in Transplantation
These data demonstrate that TheraCyte encapsulation of allogeneic cells provides robust immune protection in transplanted rhesus monkeys.
Published in Experiments in Fluids
The precision of optical imaging to study free surface dynamics is analyzed. The damping of a liquid bridge free surface oscillation is used to validate this method. Images are acquired with a digital camera at relatively high frame rates and processed by several techniques. Oscillations with amplitudes of about 20 times smaller than the pixel size...
Published in Annals of the New York Academy of Sciences
The rapid advancement of neuroimaging methodology and its growing availability has transformed neuroscience research. The answers to many questions that we ask about how the brain is organized depend on the quality of data that we are able to obtain about the locations, dynamics, fluctuations, magnitudes, and types of brain activity and structural ...
Published in Journal of Translational Medicine
BackgroundThe development of postoperative granulation tissue is one of the main postoperative risks after lumbar spine surgery. This granulation tissue may lead to persistent or new clinical symptoms or complicate a follow up surgery. A sensitive non-invasive imaging technique, that could diagnose this granulation tissue at the bedside, would help...
Published in Biomacromolecules
We report the synthesis of PEG-coated, core-cross-linked polymeric micelles (CCPMs) derived from an amine-terminated amphiphilic block copolymer, poly(PEG-methacrylate)-b-poly(triethoxysilyl propylmethacrylate). The block copolymer self-assembled to form micellar nanoparticles, and a Cy-7-like near-infrared fluorescence (NIRF) dye was entrapped in ...
Published in Journal of biomedical optics
We demonstrate how to construct calibrated, stable, and inexpensive tissue-like phantoms for near-IR (NIR) fluorescence imaging applications. The bulk phantom material is composed of gelatin, intralipid, hemoglobin, and indocyanine green (ICG). Absorbance, scatter, background fluorescence, and texture can be tuned as desired. NIR fluorescent inclus...
Published in Cerebral cortex (New York, N.Y. : 1991)
While the receptive field properties of single neurons in the inferior parietal cortex have been quantitatively described from numerous electrical measurements, the visual topography of area 7a and the adjacent dorsal prelunate area (DP) remains unknown. This lacuna may be a technical byproduct of the difficulty of reconstructing tens to hundreds o...
Published in Analytical and Bioanalytical Chemistry
Optical imaging of specific molecular targets and pathways in vivo has recently become possible through continued developments in imaging equipment, reconstruction algorithms, and more importantly the availability of imaging reporter molecules. These reporter molecules encompass photoproteins expressed in vivo and exogenously administered probes de...
La problématique qui a motivé cette étude est celle de la représentation et du traitement de l'information dans le néocortex. On s'intéresse en particulier à l'hypothèse selon laquelle l'information sensorielle est représentée par un "code" spatio-temporel dans l'activité coopérative des populations neuronales. Cette étude est fondamentale pour le ...
Im Rahmen dieser Arbeit wurde ein Algorithmus zur blinden Quellentrennung mit dem Namen ''Extended Spatial Decorrelation (ESD)'' entwickelt und mit bekannten ''Independent Component Analysis (ICA)'' Verfahren bezüglich der Robustheit gegen statistische Abhängigkeit der Quellen und Rauschen anhand von künstlichen Testdaten und ''Optical Imaging (OI)...
