Aggarwal, Nupur Barclay, William Shinohara, Mari L.
Published in
Current Clinical Microbiology Reports
Purpose of ReviewDespite the increasing number of clinical reports on immune reconstitution inflammatory syndrome (IRIS), mechanistic understanding of IRIS is still largely limited. The main focus of this review is to summarize animal studies, which were performed to better understand the cellular and molecular mechanisms underlying the pathology o...
Zakharia, Kais Tabibian, James H
Published in
Journal of community medicine (Reno, Nev.)
Infection is the second most common cause of esophagitis, second only to gastroesophageal reflux, and represents a clinically important disorder. Immunosuppressed patients are at highest risk for infectious esophagitis, with CANDIDA, herpes simplex virus, and cytomegalovirus being the most common causative microorganisms. Here we provide a brief cl...
Danziger-Isakov, Lara
Published in
Infectious disease clinics of North America
Biologics target various pathways to modify immunologic activity. Biologic use to treat pediatric patients continues to expand; but limited data exist regarding infectious complications of these agents, especially for newer agents. Infectious events reported in the literature for pediatric patients indicate that a variety of bacterial, mycobacteria...
Sharma, Ruchi Kanne, Jeffrey P. Martin, Maria D. Meyer, Cristopher A.
Published in
Current Radiology Reports
Purpose of ReviewThe purpose of this review is to summarize the imaging findings of thoracic infections occurring in immunocompromised patients. Lung infection remains one of the most common complications in immunocompromised patients and is one of the major contributors to morbidity and mortality. Imaging examinations are frequently performed in i...
Boix, Francisco Llorente, Santiago Eguía, Jorge Gonzalez-Martinez, Gema Alfaro, Rafael Galián, Jose A Campillo, Jose A Moya-Quiles, María Rosa Minguela, Alfredo Pons, Jose A
...
Published in
World journal of transplantation
To validate intracellular cytokine production functional assay as means of cell-mediated immunity monitoring of post-transplant patients with opportunistic infection (OI). Intracellular cytokine-producing CD4+ and CD8+ T-cell monitoring was carried out in 30 liver transplant (LTr) and 31 kidney transplant (KTr) recipients from 2010 to 2012. Patient...
Tudesq, Jean-Jacques Cartron, Guillaume Riviere, Sophie Morquin, David Iordache, Laura Mahr, Alfred Pourcher, Valerie Klouche, Kada Cerutti, Diane Le Quellec, Alain
...
Rituximab is commonly used for the treatment of hematological malignancies and autoimmune diseases. Despite a reputation for good tolerance, case-series and registries reported rituximab-related infections of variable severity including opportunistic infections. We aimed at describing the natural history of infectious events (IE) after treatment by...
AbdelRazek, Mahmoud A. Gutierrez, Jose Mampre, David Cervantes-Arslanian, Anna Ormseth, Cora Haussen, Diogo Thakur, Kiran T. Lyons, Jennifer L. Smith, Bryan R. O’Connor, Owen
...
Published in
Stroke
Background and Purpose HIV infection has been shown to increase both ischemic and hemorrhagic stroke risks, but there are limited data on the safety and outcomes of intravenous (IV) thrombolysis with tissue plasminogen activator (tPA) for acute ischemic stroke (AIS) in HIV-infected patients. Methods A retrospective chart review of IV tPA-treated HI...
Assiri, Rasha
Published in
Sudanese journal of paediatrics
A 7-month-old male baby presented to the pediatric hematology unit for investigations of recurrent episodes of neutropenia associated with fever and respiratory distress. He developed a stormy course with severe respiratory distress syndrome associated with opportunistic polymicrobial pulmonary infections. Extensive radiological, microbiological, a...
Raab, Peter Sedlacek, Ludwig Buchholz, Stefanie Stolle, Stefan Lanfermann, H.
Published in
Clinical Neuroradiology
PurposeThe aim of this study was to describe radiological imaging findings of a complicated sinusitis, which should raise the suspicion of rhino-orbital-cerebral mucormycosis as being the underlying cause.MethodsIn this retrospective analysis, we describe the cases and imaging findings of 8 patients with proven mucormycosis. These patients presente...
Jain, Chakresh Kumar Wadhwa, Gulshan
Published in
Current trends in Bioinformatics: An Insight
There is steady rise in the number of immunocompromised population due to increased use of potent immunosuppression therapies. This is associated with increased risk of acquiring fungal opportunistic infections in immunocompromised patients which account for high morbidity and mortality rates, if left untreated. The conventional antifungal drugs to...