Don't trust a book by its cover
Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of...
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peer reviewed / Age-related macular degeneration (AMD) is a worldwide leading cause of blindness affecting individuals over 50 years old. The most aggressive form, wet AMD, is characterized by choroidal neovascularization (CNV) and inflammation involving microglia recruitment. By using a laser-induced CNV mouse model, we provide evidence for a key ...
Pyruvate dehydrogenase kinase/lactate axis: a therapeutic target for neovascular age-related macular degeneration identi...
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peer reviewed / Neovascular age-related macular degeneration (nAMD) is the leading cause of blindness in aging populations. Here, we applied metabolomics to human sera of patients with nAMD during an active (exudative) phase of the pathology and found higher lactate levels and a shift in the lipoprotein profile (increased VLDL-LDL/HDL ratio). Simil...
[Delays in the management of ocular complications of giant cell arteritis: A retrospective monocentric study of 33 patie...
...Published in La Revue de medecine interne
Ocular complications of giant cell arteritis (GCA) can lead to irreversible bilateral blindness and represent a therapeutic emergency. Recommendations for the management of GCA have recently been updated. The objective of the study was to evaluate delays in appropriate management of the ocular complications of GCA and its determinants. Retrospectiv...
Dérivés sanguins à usage ophtalmique : nouvelle ligne thérapeutique dans le traitement de la sécheresse oculaire
La sécheresse oculaire est une pathologie englobant de vastes notions pouvant dépasser le cadre de l’ophtalmologie. Elle est définie comme une maladie multifactorielle de la surface oculaire caractérisée par une perte de l’homéostasie du film lacrymal et accompagnée de symptômes oculaires, dans laquelle l’instabilité et l’hyperosmolarité du film la...
Ocular manifestation as first sign of Coronavirus Disease 2019 (COVID-19): Interest of telemedicine during the pandemic ...
Published in Journal Francais D'Ophtalmologie
We report here the case of a 27-year-old man who consulted by telemedicine during the Coronavirus disease 2019 (COVID-19) pandemic, due to foreign body sensation and left eye redness. Examination revealed unilateral eyelid edema and moderate conjunctival hyperemia. A few hours later, the patient experienced intense headache and developed fever, cou...
Decontamination of whole donor eye globes with a commercial antibiotic cocktail medical device
BACKGROUND : In donor cornea transplantation a decontamination step is required in order to reduce the cornea contamination. At the Eye Bank of Liege, Belgium, the decontamination is performed with 5% iodopovidone solution quick wash before dissection. AIMS: To evaluate the use of decontamination solution BASE.128 (AL.CHI.MI.A. S.r.l.) for decontam...
Conjonctivite à chlamydia trachomatis.
peer reviewed
Chirurgie de la cataracte chez les patients monophtalmes : une cohorte rétrospective de 100 patients
OBJECTIF : évaluer le déroulement et suites opératoires d’une chirurgie de la cataracte chez les patients monophtalmes.
PATIENTS ET MÉTHODES : une étude de cohorte rétrospective a été menée au sein du service d’ophtalmologie du Centre Hospitalier Universitaire Pasteur 2 de Nice. Ont été inclus tous les patients monophtalmes opérés d’une chirurgie de...
Clinical application of laser Doppler holography in ophthalmology
This PhD aimed at introducing laser Doppler holography (LDH) into the field of ophthalmology in order to image blood flow in the eye posterior pole. Perfusion abnormalities play a central role in the development of ocular pathologies, which calls for the development of suitable instruments to elucidate it. LDH had previously demonstrated its abilit...
