Zhou, Qian Xu, Wenqi Zhu, Xiaoyu Zhang, Jin Zhang, Yan Han, Yan Chen, Kai Yin, Yueping
Published in
Infection and Drug Resistance
Purpose The increasing drug resistance of Neisseria gonorrhoeae has become a serious public health concern. This study investigated N. gonorrhoeae isolates susceptibility to tetracycline antibiotics and the correlation between minimum inhibitory concentrations (MICs) of different antibiotics. The presence of resistance determinants in N. gonorrhoea...
Lin, Eric Yu Adamson, Paul C. Ha, Sung-min Klausner, Jeffrey D.
Published in
Microbiology Spectrum
Antimicrobial resistance in N. gonorrhoeae is increasing globally, and ceftriaxone is the recommended treatment for empirical therapy in most settings. Developing molecular assays to detect decreased ceftriaxone susceptibility is critical. Using PathogenWatch, a public database of N. gonorrhoeae genomes, antibiotic susceptibility data and DNA seque...
Liu, Ting Lai, Shu-yu Zhou, Wei Liu, Yan-ling Chen, Sha-sha Jiang, Yong-mei
Published in
BMC Infectious Diseases
Background The aim of this study was to analyze the present situation of Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), Mycoplasma genitalium (MG) and Neisseria gonorrhoeae (NG) infections among obstetrics and gynecological outpatients in southwest China. Methods A total of 3225 urogenital swabs were included in this study. All swabs were...
Strikić Đula, Ivana Pleić, Nikolina Babić Leko, Mirjana Gunjača, Ivana Torlak, Vesela Brdar, Dubravka Punda, Ante Polašek, Ozren Hayward, Caroline Zemunik, Tatijana
...
Published in
Biology
Thyroid dysfunction appears to be the leading endocrine disorder. We conducted a cross-sectional study on 4402 individuals from three Croatian cohorts. The aim of this study was to analyse the prevalence of diagnosed and undiagnosed hypothyroidism, hyperthyroidism (subclinical and clinical) and positive thyroid antibodies in the Croatian population...
Christodoulides, Myron
Published in
Frontiers in Cellular and Infection Microbiology
Neisseria pathogens express a Macrophage Infectivity Potentiator Protein (MIP), which belongs to the FK506 binding protein (FKBP) family of proteins that exhibit peptidyl-prolyl cis/trans isomerase (PPIase) activity. Neisseria MIP proteins are potential candidates for inclusion into vaccines for gonorrhoea caused by N. gonorrhoeae infection, and me...
Yu, Xueying Zhao, Peizhen Mai, Zhida Xu, Qingqing Chen, Wentao Wu, Zhiqiao Luo, Xiaojuan Wu, Zhizhou Liu, Xiaofeng Wu, Qian
...
Published in
Frontiers in Medicine
Leukocyte esterase test (LET) detection is a simple and inexpensive test performed by urinalysis. This study investigated the predictive value of LET for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among men attending HIV and sexually transmitted infection (HIV/STI) clinics in Guangdong Province, China. A total of 5,509 urin...
Ma, Zhihai Gharizadeh, Baback Cai, Xingsheng Li, Mengzhen Fellner, María Dolores Basiletti, Jorge Alejandro Correa, Rita Mariel Colucci, María Celeste Baldoni, Gabriela Vacchino, Martín
...
Published in
Infectious Agents and Cancer
Background Sexually transmitted infections (STIs) are prevalent throughout the world and impose a significant burden on individual health and public health systems. Missed diagnosis and late treatment of STIs can lead to serious complications such as infertility and cervical cancer. Although sexually transmitted co-infections are common, most comme...
Manoharan-Basil, Sheeba Santhini González, Natalia Laumen, Jolein Gyonne Elise Kenyon, Chris
Published in
Frontiers in Microbiology
Antimicrobial resistance in Neisseria gonorrhoeae is an important global health concern. The genetically related commensal Neisseria act as a reservoir of resistance genes, and horizontal gene transfer (HGT) has been shown to play an important role in the genesis of resistance to cephalosporins and macrolides in N. gonorrhoeae. In this study, we ev...
Schlievert, Patrick M. Kilgore, Samuel H. Benavides, Andrea Klingelhutz, Aloysius J.
Published in
Microbiology Spectrum
Many bacterial and fungal pathogens cause disease across mucosal surfaces, and to a lesser extent through skin surfaces. Pathogens that potentially cause disease vaginally across epithelial cells include Staphylococcus aureus, group A and B streptococci, Escherichia coli, Neisseria gonorrhoeae, and Candida albicans. We have previously shown that st...
Tailor, Neelam Dean, Matthew R. Dellalana, Michelle Jitendranath, Lavanya
Published in
IDCases
• Gonococcal endocarditis should be suspected in young sexually active adults with culture-negative endocarditis. • Gonococcal endocarditis is a rare but life-threatening complication of untreated disseminated gonococcal infections. • Early antibiotic therapy with a third-generation cephalosporin is recommended for gonococcal infections.