Osman, K. M. Hassan, W. M. M. Mohamed, R. A. H.
Published in
European Journal of Clinical Microbiology & Infectious Diseases
The present study was undertaken to identify and characterise integrons and integrated resistance gene cassettes among eight multidrug-resistant (MDR) Salmonella serovars isolated from humans in Egypt. Virulotyping by polymerase chain reaction (PCR) was used for the detection of the presence of virulence genes. Integron PCR was used to detect the p...
Premkumar, Lakshmanane Kurth, Fabian Neyer, Simon Schembri, Mark A Martin, Jennifer L
Published in
The Journal of biological chemistry
The multidrug resistance-encoding IncA/C conjugative plasmids disseminate antibiotic resistance genes among clinically relevant enteric bacteria. A plasmid-encoded disulfide isomerase is associated with conjugation. Sequence analysis of several IncA/C plasmids and IncA/C-related integrative and conjugative elements (ICE) from commensal and pathogen...
Oliveira dos Santos, Silvana Brezolin, Daiane Hörner, Rosmari
AIMS: To evaluate the characteristics of antimicrobial susceptibility of carbapenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa isolated from August 2011 to January 2012 from inpatients at the University Hospital of Santa Maria, Santa Maria, Rio Grande do Sul, Brazil. METHODS: A retrospective study was conducted by consulting the databa...
Akhter, Asma Imran, Mohd Akhter, Firoz
Published in
Bioinformation
EMB - Eosin methylene blue, IMViC tests - Indole, Methyl Red, Voges Proskauer and Citrate Utilization Tests, MIC - Minimum inhibitory concentration.
Peng, JinRong Qi, TingTing Liao, JinFeng Chu, BingYang Yang, Qian Qu, Ying Li, WenTing Li, He Luo, Feng Qian, ZhiYong
...
Published in
Theranostics
Photothermal therapy (PTT) is proved to be an efficient manner for superficial tumor therapy in preclinical studying. The tumor suppression of chemotherapy can be enhanced by combining with PTT. In this study, we reported a mesoporous magnetic gold "nanoclusters" (MMGNCs) structure as theranostic carrier for chemo-photothermal co-therapy. MMGNCs we...
Yamagishi, Tetsuo Sahni, Sumit Sharp, Danae M Arvind, Akanksha Jansson, Patric J Richardson, Des R
Published in
The Journal of biological chemistry
Localization of the drug transporter P-glycoprotein (Pgp) to the plasma membrane is thought to be the only contributor of Pgp-mediated multidrug resistance (MDR). However, very little work has focused on the contribution of Pgp expressed in intracellular organelles to drug resistance. This investigation describes an additional mechanism for underst...
Kumar, Yashwant Sharma, Anshu Mani, Kavaratty Raju
Published in
Tropical life sciences research
Demam kepialu masih merupakan suatu masalah kesihatan yang serius di negara-negara membangun, dan kemunculan strain rintang-multidrug (MDR) telah mengurangkan pilihan terapeutik untuk rawatan penyakit ini. National Salmonella and Escherichia Centre di Kasauli, India telah menerima sebanyak 128 pencilan Salmonella Typhi pada tahun 2008–2009. Pencila...
Lu, Wei-Dong Qin, Yong Yang, Chuang Li, Lei
OBJECTIVE: To determine whether curcumin reverses the multidrug resistance of human colon cancer cells in vitro and in vivo. METHODS: In a vincristine-resistant cell line of human colon cancer, the cell viability of curcumin-treated cells was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Rhodamine123 efflu...
Dewan, S Sahoo, T Chandra, N Varma, A
Published in
Critical Care
Wang, Ke Pei, Hao Huang, Biao Zhu, Xue Zhang, Jue Zhou, Bin Zhu, Lan Zhang, Yi Zhou, Fan-Fan
Published in
Current Microbiology
Currently the treatment of Mycobacterium tuberculosis (TB) infection is largely limited due to the prevalence of multidrug resistance strains. Over-expressing the efflux pumps such as the ATP-binding cassette (ABC) transporter has been reported to significantly contribute to its resistance to several antibiotics. This study investigated the express...