Poulton, Kate Webster, Bonnie
Published in
Analytical biochemistry
Infection with Schistosoma mansoni causes intestinal schistosomiasis, a major health problem across Africa. The accurate diagnosis of intestinal schistosomiasis is vital to inform surveillance/control programs. Diagnosis mainly relies on microscopic detection of eggs in faecal samples but many factors affect sensitivity. Molecular diagnostics are s...
Dentini, Priscila Marson, Fernando Augusto Lima Bonadia, Luciana Cardoso Bertuzzo, Carmen Sílvia Ribeiro, Antônio Fernando Levy, Carlos Emílio Ribeiro, José Dirceu
Published in
Medical Microbiology and Immunology
The Burkholderia cepacia complex (BCC) can cause a severe decline in lung function in cystic fibrosis (CF). Our objective was to determine the BCC prevalence and to evaluate its clinical impact on CF. Clinical and laboratory variables were determined for CF patients with BCC (Group-A = 50 patients) and without BCC (Group-B = 134 patients). The micr...
Nadeali, Zakiye Vallian, Sadeq
Published in
Iranian journal of basic medical sciences
Altogether, the data suggested that rs4148326 and rs4124874 could be introduced as informative markers for molecular diagnosis of Crigler-Najjar type 1 and 2 and Gilbert syndrome in the Iranian population.
Gay-Andrieu, Françoise Magassouba, N'Fally Picot, Valentina Phillips, Cynthia L Peyrefitte, Christophe N Dacosta, Brigitte Doré, Ahmadou Kourouma, Fode Ligeon-Ligeonnet, Véronique Gauby, Corentin
...
Published in
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
This study showed that the FilmArray BioThreat-E test performs comparably to conventional molecular tests under field conditions, providing results and interpretation in approximately 1h. Due to its operational characteristics, it can be easily deployed in the field during an epidemic and could also be a useful tool for post-outbreak surveillance.
Szemiako, Kasjan Śledzińska, Anna Krawczyk, Beata
Published in
Journal of Applied Genetics
Candida sp. have been responsible for an increasing number of infections, especially in patients with immunodeficiency. Species-specific differentiation of Candida sp. is difficult in routine diagnosis. This identification can have a highly significant association in therapy and prophylaxis. This work has shown a new application of the terminal res...
Darling, David Luxmanan, Carthika O’Sullivan, Paul Lough, Tony Suttie, James
Published in
Advances in Therapy
IntroductionThis study aimed to demonstrate the clinical utility of non-invasive multigene Cxbladder urine tests in reducing the overall number of diagnostic tests and invasive procedures used in the clinical evaluation of patients presenting with microhematuria, a key symptom of urothelial carcinoma (UC). There is a belief that using non-invasive ...
Lamb, Laura E. Bartolone, Sarah N. Kutluay, Sebla B. Robledo, Daniela Porras, Alexandra Plata, Mauricio Chancellor, Michael B.
Published in
International Urology and Nephrology
Zika virus (ZIKV) infection is an emerging global health concern, and diagnostic recommendations are currently developing based on new information. Several case or small sample size studies using both urine and blood samples suggest that ZIKV RNA can be detected at higher levels and for a longer time after onset of infection in urine compared to bl...
Opota, O Senn, L Prod'hom, G Mazza-Stalder, J Tissot, F Greub, G Jaton, K
Published in
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Airborne precautions are required at hospital admission for patients with suspected pulmonary tuberculosis. The isolation is maintained until 3 serially collected sputum smears are acid-fast bacilli negative, a time- and labor-intensive method with limited sensitivity and specificity, which has a great impact on patient flow management. We evaluate...
Kim, Jung Eun Choi, Ji Hye Colas, Marion Kim, Dong Ha Lee, Hyukjin
Published in
Biosensors & bioelectronics
The properties of gold nanomaterials are particularly of interest to many researchers, since they show unique physiochemical properties such as optical adsorption of specific wavelength of light, high electrical conductance with rich surface electrons, and facile surface modification with sulfhydryl groups. These properties have facilitated the use...
Hu, Zhanzhi Whitney, Duncan Anderson, Jessica R. Cao, Manqiu Ho, Christine Choi, Yoonha Huang, Jing Frink, Robert Smith, Kate Porta Monroe, Robert
...
Published in
BMC Cancer
BackgroundThe current standard practice of lung lesion diagnosis often leads to inconclusive results, requiring additional diagnostic follow up procedures that are invasive and often unnecessary due to the high benign rate in such lesions (Chest 143:e78S-e92, 2013). The Percepta bronchial genomic classifier was developed and clinically validated to...
