Published in International Journal of Molecular Sciences
Seizures are common in patients with high-grade gliomas (30–60%) and approximately 15–30% of glioblastoma (GB) patients develop drug-resistant epilepsy. Reliable animal models are needed to develop adequate treatments for glioma-related epilepsy. Therefore, fifteen rats were inoculated with F98 GB cells (GB group) and four rats with vehicle only (c...
Published in International Journal of Molecular Sciences
Contrary to the conserved Elongator composition in yeast, animals, and plants, molecular functions and catalytic activities of the complex remain controversial. Elongator was identified as a component of elongating RNA polymerase II holoenzyme in yeast, animals, and plants. Furthermore, it was suggested that Elonagtor facilitates elongation of tran...
Published in iScience
Biological Sciences; Molecular Biology; Molecular Mechanism of Gene Regulation
Published in iScience
Molecular Biology; Developmental Biology; Genomics
Published in iScience
Medical Biochemistry; Molecular Biology; Cancer
Published in iScience
Immunology ; Molecular Biology; Neuroscience
Published in iScience
Molecular Biology; Neuroscience; Genetic Engineering
The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide, reaching near fixation in a matter of months. Here we show that D614G was more infectious than the ancestral form on human lung cells, colon cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE2 orthologs from various mammals, i...
Published in iScience
Molecular Biology; Virology
Published in iScience
Biological Sciences; Molecular Biology; Immunology; Microbiome
