Published in Communications Biology
Cryo-EM structures, MD simulations, and biochemical assays of human multidrug resistance-associated protein 4 in apo inward-open, ATP-bound outward-open, PGE1 substrate-bound, and sulindac inhibitor-bound states provide insights into substrate transport and inhibition mechanism.
Published in Journal of colloid and interface science
The maintenance of plasma membrane structure is vital for the viability of cells. Disruption of this structure can lead to cell death. One important example is the macroscopic phase separation observed during dehydration associated with desiccation and freezing, often leading to loss of permeability and cell death. It has previously been shown that...
Published in bioRxiv
Semipermeable membranes are a key feature of all living organisms. While specialized membrane transporters in cells can import otherwise impermeable nutrients, the earliest cells would have lacked a mechanism to import nutrients rapidly under nutrient-rich circumstances. Using both experiments and simulations, we find that a process akin to passive...
Tesis por compendio / [ES] El desarrollo de membranas poliméricas capaces de actuar como electrolito en pilas de combustible tipo PEMFC a temperaturas intermedias constituye uno de los principales retos para conseguir la generación eficiente de energía por medio de estos dispositivos. Actualmente, las membranas basadas en polímeros perfluorosulfona...
Published in iScience
Drug delivery system; Health technology; Membranes
Published in iScience
Applied sciences; Composite materials; Membranes
Published in Marine environmental research
In the open ocean and particularly in iron (Fe)-limited environment, copper (Cu) deficiency might limit the growth of phytoplankton species. Cu is an essential trace metal used in electron-transfer reactions, such as respiration and photosynthesis, when bound to specific enzymes. Some phytoplankton species, such as the diatom Pseudo-nitzschia spp. ...
Published in Mikrochimica Acta
Carbon nanomaterials (CNMs) have some excellent properties that make them ideal candidates as sorbents for solid-phase extraction (SPE). However, practical difficulties related to their handling (dispersion in the atmosphere, bundling phenomena, reduced adsorption capability, sorbent loss in cartridge/column format, etc.) have hindered their direct...
Published in iScience
Membranes; Applied sciences
