Clinical research was carried out to assess the effects of 2 longacting injectable contraceptives on the ovaries and uteri of female virgin rats. 2 different doses of DMPA (depo-medroxyprogesterone acetate) and NE (norethisterone enanthate) and 2 control substances were used in the study. The laboratory procedures employed are explained and the res...
Clinical studies were carried out with laboratory female rats to ascertain the effects of daily dosing with MPA (medroxyprogesterone acetate). Some of the rats received .8 mg MPA in 1.4 ml acqueous suspension. The others received 2 mg MPA in intramuscular injections. The doses used were those necessary for estrus synchronisation. Body weight was in...
The immunosuppressive effects of MPA (medroxyprogesterone acetate) were tested in clinical studies with laboratory dogs and rabbits. The laboratory procedures employed in the studies are explained and results are tabulated and graphed. 2 microscopic photographs illustrate the observed effects. MPA significantly prolonged the survival of dogs with r...