Les méningiomes représentent 30% des tumeurs cérébrales primitives, et correspondent dans 90% des cas à des tumeurs bénignes. Le pronostic dépend essentiellement du grade histologique, de la localisation et de la qualité de l’exérèse chirurgicale. Plus récemment, il a été décrit d’autres facteurs pronostiques comme les altérations moléculaires ou l...
Published in Gynecologie, obstetrique, fertilite & senologie
International audience
Published in Journal francais d'ophtalmologie
Meningiomas represent about 20% of intracranial tumors. Involvement of the medial sphenoid wing includes anterior clinoid, cavernous sinus and superior orbital fissure meningiomas. Due to the proximity of these tumors to the optic nerve, typically progressive unilateral vision loss, over several months to years, is the classic clinical presentation...
Published in Neuro-Chirurgie
Neurofibromatosis type 2 is characterized by the presence of bilateral vestibular schwannomas. However, other nervous system tumors may also occur. Therefore, the management of NF2 patients is complex and requires a multidisciplinary discussion in a specialized center. All recent articles concerning tumors other than vestibular schwannoma in NF2 di...
Introduction : Les méningiomes sont des tumeurs extraparenchymateuses développées aux dépens des cellules arachnoïdiennes (villosités), et constitue chez l’adulte, la tumeur intracrânienne la plus fréquente. Bien que ces tumeurs soient le plus souvent bénignes, certains méningiomes peuvent poser des problèmes aux neurochirurgiens pour plusieurs rai...
Published in Neuro-Chirurgie
New advances have recently been made in the field of molecular genetics and mouse modeling of meningiomas, opening new perspectives for future treatments. Recent genome-wide genotyping and exome sequencing studies have confirmed the pivotal role of NF2 in meningioma tumorigenesis, concerning roughly half of the tumors, and unraveled new mutations i...
Published in Neuro-Chirurgie
Given the number of meningiomas not histologically-validated, we can estimate that the gross incidence rate for meningiomas operated in France is about 4.2 per 100,000 person/year. To our knowledge, this work is the most important study evaluating the different subtypes of meningiomas and it validates the relevance of histological databases for cen...
Published in Neuro-Chirurgie
This review focuses on the role of radiosurgery and fractionated radiotherapy in the management of intracranial meningiomas, which are the most common benign intracranial tumors. Whenever feasible, surgery remains a cornerstone of treatment in effective health care treatment where modern radiotherapy plays an important role. Irradiation can be prop...
INTRODUCTION : L'application PELICAN (« Partager Efficacement en Laboratoire les Informations des Comptes rendus Anatomopathologiques ») est un outil permettant de générer des comptes rendus standardisés et de créer des bases de données utilisables à viséescientifique. Cette application est utilisée dans notre laboratoire depuis 2014 en neuropathol...
