van Baal, JOAM Van de Vijver, Koen Coffelt, SB van der Noort, V van Driel, WJ Kenter, GG Buist, MR Lok, CAR
Objective: The use of lymph node sampling during staging procedures in clinical early-stage mucinous ovarian carcinoma (MOC) is an ongoing matter of debate. Furthermore, the incidence of lymph node metastases (LNM) in MOC in relation to tumour grade (G) is unknown. We aimed to determine the incidence of LNM in clinical early-stage MOC per tumour gr...
Lago, V Minig, L Fotopoulou, C
Objectives: This study aimed to determine the incidence of lymph node (LN) metastases in presumed stage I-II low-grade epithelial ovarian cancer (EOC). Methods: Eligible studies were identified from MEDLINE and EMBASE (time frame, 2015–1975), that analyzed patients with clinical or radiologic presumed early-stage EOC who underwent a complete pelvic...
Speth, Stéphanie CJM Kruitwagen, Roy FPM Kleppe, Marjolein Pooters, Ivo NA Van Gorp, Toon Slangen, Brigitte FM Brans, Boudewijn
Tracer injection into ovarian ligaments has been shown to detect sentinel nodes (SNs) in patients with ovarian cancer. To determine the possibility that SNs are missed, this feasibility study compared their detection during surgery with their detection on postoperative SPECT/CT. Methods: In 8 patients (with either ovarian or endometrial cancer), af...
Thoen, Hendrik Ceelen, Wim Boterberg, Tom Van Daele, Elke Pattyn, Piet
Published in
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Neoadjuvant chemoradiotherapy followed by Ivor-Lewis esophagectomy yields excellent in-field control, as only a clear minority (7.8%) of patients developed a relapse in the RTV. In-field recurrence is associated with widespread tumor dissemination and poor pathological response to neoadjuvant treatment.
Van Praet, Charles Decaestecker, Karel FONTEYNE, VALERIE Ost, Piet De Visschere, Pieter VERSCHUERE, STEPHANIE Rottey, Sylvie Lumen, Nicolaas
OBJECTIVES: To prospectively assess contemporary complication rates of minimally-invasive staging pelvic lymph node dissection before curative radiotherapy for prostate cancer using a standardized classification. METHODS: A total of 100 prostate cancer patients underwent laparoscopic or robot-assisted pelvic lymph node dissection (95% extended). Su...
Kleppe, Marjolein Van Gorp, Toon Slangen, Brigitte FM Kruse, Arnold J Brans, Boudewijn Pooters, Ivo NA Van de Vijver, Koen K Kruitwagen, Roy FPM
Published in
Trials
BackgroundThe concept of sentinel lymph node surgery is to determine whether the cancer has spread to the very first lymph node or sentinel node. If the sentinel node does not contain cancer, then there is a high likelihood that the cancer has not spread to other lymph nodes. The sentinel node technique has been proven to be effective in different ...
VAN OOSTRUM, NOORTJE Makar, Amin Van den Broecke, Rudy
The aim of this study was to assess the value of sentinel lymph node procedures in gynecologic cancers. A systematic literature overview, using the PubMed database, was performed. In early stage vulvar, endometrial and cervical cancer, lymph node status is the most important prognostic factor. Lymphadenectomy, performed for adequate staging, is ass...
Coosemans, An; 52883; Van Calster, Ben; 22832; Verbist, Godelieve; 26329; Moerman, Philippe; 12196; Vergote, Ignace; 2443; Van Gool, Stefaan; 11326; Amant, Frédéric; 43256;
Introduction: Wilms tumor gene 1 (WT1) contributes to uterine sarcoma tumor biology. In this study, we aimed to clarify the prognostic value of WT1. Methods: A retrospective clinical and histopathological review of 71 women with high-grade uterine sarcoma (leiomyosarcoma [n = 24], undifferentiated sarcoma [n = 9]), and carcinosarcoma (n = 38) was p...
COIMBRA, F. J. F. COSTA JR., W. L. MONTAGNINI, A. L. DINIZ, A. L. RIBEIRO, H. S. C. SILVA, M. J. B. BEGNAMI, M. F. S.
Background: Depth of tumor invasion (T-category) and the number of metastatic lymph nodes (N-category) are the most important prognostic factors in patients with gastric cancer. Recently, the ratio between metastatic and dissected lymph nodes (N-ratio) has been established as one. The aim of this study is to evaluate the impact of N-ratio and its i...
COIMBRA, F. J. F. COSTA JR., W. L. MONTAGNINI, A. L. DINIZ, A. L. RIBEIRO, H. S. C. SILVA, M. J. B. BEGNAMI, M. F. S.
Background: Depth of tumor invasion (T-category) and the number of metastatic lymph nodes (N-category) are the most important prognostic factors in patients with gastric cancer. Recently, the ratio between metastatic and dissected lymph nodes (N-ratio) has been established as one. The aim of this study is to evaluate the impact of N-ratio and its i...