The detrimental effects of iron on the joint: a comparison between haemochromatosis and haemophilia.
Published in Journal of clinical pathology
Joint damage due to (recurrent) joint bleeding in haemophilia causes major morbidity. Although the exact pathogenesis has not been fully elucidated, a central role for iron is hypothesised. Likewise, in hereditary haemochromatosis joint destruction is caused by iron overload. A comparison between these types of arthropathy could provide more insigh...