Schupbach, Ryan R Bousum, John M Miller, Michael J
Published in
Pharmacy practice
Although anticoagulation guidelines now emphasize patient self-management (PSM) only, optimal PST remains an integral process in PSM delivery. In the patients studied, the results of this analysis suggest that PST at the IHS facility provided a convenient, alternative method for management of chronic warfarin therapy for qualified patients. More th...
Karlsson, Jessica
Introduction: It is recommended to place all the vacuum tubes directly on a sample cradle after vein puncture to prevent analytic error. This recommendation is not always easy to follow because the samples are taken by different professionals under different situations. The three most common analyses, platelets count, haemoglobin and prothrombin t...
Stafford, L Peterson, GM Bereznicki, LRE Jackson, SL Van Tienen, EC Angley, MT Bajorek, BV McLachlan, AJ Mullan, JR Misan, GMH
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BACKGROUND: Warfarin remains a high-risk drug for adverse events, especially following discharge from the hospital. New approaches are needed to minimize the potential for adverse outcomes during this period. OBJECTIVE: To evaluate the clinical outcomes of a collaborative, home-based postdischarge warfarin management service adapted from the Austra...
Ávila, Christiane Wahast Aliti, Graziella Badin Feijó, Maria Karolina Ferreira Rabelo, Eneida Rejane
Cross-sectional study developed to relate the international normalized ratio (INR), used as a parameter to monitor the levels of blood clotting, stability to adherence, age, level of education, socioeconomic level, interaction with other drugs, comorbidities, vitamin K intake, anticoagulation time and drug cost. 156 patients were included, mean age...
Wong, Yun
Published in
Clinical medicine insights. Case reports
ICH patients can present with no neurological signs. In OAT patients with headache, INR must be established; if ≥3.0, normalization of INR and head CT are essential. PCC is the best option to rapidly reverse anticoagulation and correct INR pre-surgery.
Armero Simarro, Juan Miguel Romero Cebrián, Mª Aranzazu Ayuso Raya, M.C. Arias Alaminos, María Pérez López, Nieves Escobar Rabadán, Francisco
Background: After taking control of oral anticoagulant therapy in our health center it became necessary to detect possible differences with regard to hospital monitoring. The aim of our study was to determine the variability in the International Normalized Ratio (INR) values of patients on oral anticoagulant therapy (OAT), and the possible relation...
Faivre, Magalie Peltié, Philippe Planat-Chrétien, Anne Cosnier, Marie-Line Cubizolles, Myriam Nougier, Christophe Negrier, Claude Pouteau, Patrick
We report a new technique to measure coagulation dynamics on whole-blood samples. The method relies on the analysis of the speckle figure resulting from a whole-blood sample mixed with coagulation reagent and introduced in a thin chamber illuminated with a coherent light. A dynamic study of the speckle reveals a typical behavior due to coagulation....
Camm, A John Kirchhof, Paulus Lip, Gregory Y H Schotten, Ulrich Savelieva, Irene Ernst, Sabine Van Gelder, Isabelle C Al-Attar, Nawwar Hindricks, Gerhard Prendergast, Bernard
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Peer reviewed
Kangelaris, Kirsten Neudoerffer Bent, Stephen Nussbaum, Robert L Garcia, David A Tice, Jeffrey A
BackgroundGenotype-guided initial warfarin dosing may reduce over-anticoagulation and serious bleeding compared to a one-dose-fits-all dosing method.ObjectiveThe objective of this review was to investigate the safety and efficacy of genotype-guided dosing of warfarin in reducing the occurrence of serious bleeding events and over-anticoagulation.Dat...
Walker, Gennyne Mandagere, Arun Dufton, Christopher Venitz, Jürgen
Published in
British journal of clinical pharmacology
Multiple doses of ambrisentan had no clinically relevant effects on the pharmacokinetics and pharmacodynamics of a single dose of warfarin. Therefore, significant dose adjustments of either drug are unlikely to be required with co-administration.
