Gupta, Bharat Sawhney, Anshul Patil, Neha Yadav, Manoj Tripathi, Shashank Sinha, Saurabh Sharma, Saurabh Gupta, Saurabh
Published in
Journal of clinical and diagnostic research : JCDR
Periodontitis can be defined as a local inflammatory process which mediates destruction of periodontal tissues & is triggered by bacterial insult. In periodontal infections, the levels of C reactive proteins are elevated as compared to the levels in a periodontally healthy individual. The study was done to determine the relative levels of serum CRP...
Kirschke, J. Hessam, S. Bechara, F. G.
Published in
coloproctology
Hidradenitis suppurativa/Acne inversa (HS/AI) ist eine chronische, inflammatorische Hauterkrankung, die sich durch schmerzhafte Knoten, Abszesse, Fisteln und Vernarbungen auszeichnet und zu deutlichen funktionellen sowie psychologischen Beeinträchtigungen bei den betroffenen Patienten führen kann. Es vergehen oft Jahre, bis die richtige Diagnose ge...
Patyk, Mateusz Obojski, Andrzej Gojny, Łukasz Panaszek, Bernard Zaleska-Dorobisz, Urszula
Published in
Advances in experimental medicine and biology
Asthma is a chronic inflammatory obstructive airways disease. The disease occurs regardless of age and manifests with cough, attacks of breathlessness, and tightness in the chest. The pathophysiology of asthma is complex and still not fully understood. It is essential to find answers concerning the role of each part of the bronchial tree in asthma,...
Ramonda, Roberta Favero, Marta Vio, Stefania Lacognata, Carmelo Frallonardo, Paola Belluzzi, Elisa Campana, Carla Lorenzin, Mariagrazia Ortolan, Augusta Angelini, Federico
...
Published in
Clinical Rheumatology
This study aimed to apply the recently proposed Oslo hand osteoarthritis magnetic resonance imaging (MRI) scoring system to evaluate MRI findings in a cohort of patients affected by long-standing erosive hand osteoarthritis (EHOA). Eleven female EHOA patients (median 59 [interquartile range 62–52] years, disease duration 9.5 [interquartile range 13...
Yang, Yi Feng, Juan Lü, Silin Wang, Xian
Published in
Science Bulletin
Energy homeostasis is essential for maintaining cell survival and regular functions, and the loss of energy homeostasis may result in a variety of diseases. In this review, we focus on the roles and regulatory mechanisms of T lymphocytes energy metabolism in its activation, differentiation and physiological function. We also discuss the significanc...
Gardiner, Clair M Mills, Kingston H G
Published in
Seminars in immunology
Immunological memory mediated by antigen-specific T and B cells is the foundation of adaptive immunity and is fundamental to the heightened and rapid protective immune response induced by vaccination or following re-infection with the same pathogen. While the innate immune system has classically been considered to be non-specific and devoid of memo...
Hwang, Da-Eun Choi, Jung-Min Yang, Chul-Su Lee, Joong-Jae Heu, Woosung Jo, Eun-Kyeong Kim, Hak-Sung
Published in
Biochemical and biophysical research communications
The strongest anaphylatoxin, C5a, plays a critical role in the proinflammatory responses, causing the pathogenesis of a number of inflammatory diseases including sepsis, asthma, and rheumatoid arthritis. Inhibitors of C5a thus have great potential as therapeutics for various inflammatory disorders. Herein, we present the development of a high-affin...
Bitzinger, Diane I Gruber, Michael Tümmler, Simon Michels, Bernhard Bundscherer, Anika Hopf, Susanne Trabold, Benedikt Graf, Bernhard M Zausig, York A
Published in
Neuropharmacology
Previous and more recent studies show that cholinesterase inhibitors (ChE-Is) are an important possibility for therapeutic intervention in Alzheimer's Disease, sepsis and other inflammatory syndromes. ChE-Is maintain high levels of acetylcholine (ACh) determining beneficial effects on the disease process. Despite numerous efforts to identify the ap...
Martínez López, Juan Antonio García Vivar, M Luz Cáliz, Rafael Freire, Mercedes Galindo, María Hernández, Maria Victoria López Longo, Francisco Javier Martínez Taboada, Víctor Pego Reigosa, Jose María Rubio, Esteban
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Published in
Reumatologia clinica
To develop recommendations on the evaluation and management of patients with rheumatic autoimmune and inflammatory diseases during the reproductive age, pregnancy, post-partum and breastfeeding based on the best evidence and experience. Recommendations were generated using nominal group and Delphi techniques. An expert panel of 12 rheumatologists w...
Canzonieri, Elena De Candia, Cristina Tarascio, Salvatore Giamporcaro, Silvia Lumera, Giovanni RiganoG, iuseppe Incognito, Carmela Privitera, Filippo Guarnaccia, Agata Foti Pietro, Valerio
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Published in
Toxicology reports
Statins (S) are widely used drugs for cardiovascular prevention however their utilization may cause a various grade of muscle toxicity. Sometime S discontinuation alone is not sufficient to revert muscle injury and this can evolve in serious inflammatory muscle disease. In this case immunosuppressive medications are required to achieve remission. T...
