Published in Fresenius' Journal of Analytical Chemistry
Modern measurement systems for food components often require use of ever smaller sample sizes, down to mg for some new microtechniques, which puts a stronger demand on development of reference materials with defined homogeneity for subsampling. One approach to evaluate the homogeneity of materials is the characterization of sampling constants, defi...
Published in Lipids
The addition of long-chain polyunsaturated fatty acids (LCP: C20, and C22) to infant formula may permit fatty acid accretion rates similar to breast-fed infants, and may have long-term outcome benefits, such as improved visual acuity and cognitive development. Although fish oil may provide a source of n-3 LCP, sources of n-6 LCP have been more diff...
Published in European Journal of Clinical Microbiology and Infectious Diseases
An outbreak of food poisoning involving most autonomous Spanish communities was detected in the first half of 1994. The causative food was infant formula milk contaminated by lactose-fermentingSalmonella virchow. It was not possible to isolate the causative strain from the manufacturer's facilities. During the same period of time, there was a signi...
Published in Journal of Radioanalytical and Nuclear Chemistry
Iodine is an essential nutrient in the human diet. Its primary role is expressed as a component of thyroxine (T4) and the corresponding deiodinated triiodothyronine (T3) hormones produced by the thyroid as part of the system that regulates growth, mental development and metabolism. The recommended daily allowance (RDA) for iodine ranges from 50 μg/...
Published in Lipids
Sufficient availability of both n-3 and n-6 long-chain polyunsaturated fatty acids (LCPUFA) is required for optimal structural and functional development in infancy. The question has been raised as to whether infant formulae would benefit from enrichment with 20 and 22 carbon fatty acids. To address this issue, we determined the effect of fish oil ...
Published in Lipids
The purpose of this workshop at the American Oil Chemists’ Society Symposium, “PUFA in Infant Nutrition: Consensus and Controversies”, was to enumerate the safety issues raised by the prospect of supplementing infant formulas with long-chain polyunsaturated fatty acids (LC-PUFA), to evaluate the evidence that these concerns are problematical, or th...
Published in Lipids
While the scientific evaluation of the physiologic effects, potential benefits, and risks of dietary preformed long-chain polyunsaturated fatty acids (LCPUFA) for infants have been discussed elsewhere, this manuscript addresses some of the resulting consequences and challenges of interpreting the available knowledge from the perspective of recommen...
Published in Lipids
The importance of n−6 and n−3 polyunsaturated fatty acids (PUFA) in neonatal development, particularly with respect to the developing brain and retina, is well known. This review combines recent information from basic science and clinical studies to highlight recent advances in knowledge on PUFA metabolism and areas where research is still needed o...
Published in Lipids
The rationale for randomized trials designed to measure the effects of variable docosahexaenoic acid (DHA) status on neurodevelopment in human infants came from earlier studies of neurodevelopment in animals that were deficient in DHA owing to diets low in α-linolenic acid. The session on neurodevelopment looked at the results of these animal studi...
Published in Lipids
Eicosanoids are highly active lipid mediators in physiologic and pathologic processes, with their effects ranging from cytoprotection and vasoactivity to modulation of inflammatory and proliferative reactions. Generation of eicosanoids can be affected by changes in the pools of their precursors, the long-chain polyunsaturated fatty acids (LCPUFA). ...
