Zhang, Ruijie Huo, Xiankai Wang, Qian Zhang, Juntao Duan, Shaofeng Zhang, Quan Zhang, Shicai
Published in
Journal of cancer research and clinical oncology
To explore the feasibility and performance of machine learning-based radiomics models in predicting thyroid transcription factor-1 (TTF-1) expression in non-small cell lung cancer (NSCLC). A total of 227 NSCLC patients were included in this retrospective study and divided into the training set and test set with a ratio of 8:2 randomly. Lung tumors ...
Antony, Gisha Rose Augustine, Paul Parambil, Sulfath Thottungal Littleflower, Ajeesh Babu Kattoor, Jayasree Krishna, K M Jagathnath Subhadradevi, Lakshmi
Published in
Clinical and experimental medicine
Antitumor immune evasion is a hallmark for the development and progression of cancer. Tumor cells adopt various mechanisms to escape the host immune system recognition. One such mechanism is the over expression of programmed death ligand (PD-L1), a negative T cell regulatory molecule. Because PD-L1 overexpression causes resistance to chemotherapeut...
Hassan, Gihan S Helal, Mai B Ibrahim, H F
Published in
Odontology
This study aimed to assess the histological changes in the maxillary sinus and its adjacent dental tissues as pulp and periodontal ligament during pregnancy and investigate the role of estrogen hormone in these changes through the detection of estrogen receptors in these tissues. Sixteen adult female rats were used and were allocated into two group...
Memary, Elham Imani, Alireza Arhamidolatabadi, Ali Fadavi, Parvaneh Aghajani, Marjan Mohebzadeh, Farnoosh Shahverdi-Shahraki, Mohammad Dabbagh, Ali Mirkheshti, Alirza Shirian, Sadegh
...
Published in
Cellular and molecular neurobiology
Although advances in diagnosis and treatment of cardiac arrest (CA) could improve neurological outcomes after cardiopulmonary resuscitation (CPR), survival rate and neurological outcome after CA and CPR remain poor. This study aimed to investigate the effect of epinephrine (EP) alone and EP in combination with methylprednisolone (MP) (EP + MP) on s...
Kattapuram, Meera Shabet, Christina Austin, Sarah Jacobs, Michelle F Koeppe, Erika Smith, Emily H Lowe, Lori Else, Tobias Cha, Kelly B
Published in
Familial cancer
Immunohistochemistry (IHC) of cutaneous sebaceous lesions (SL) can be used to screen patients for Lynch syndrome (LS). There is little data on rates of genetic referral and outcomes of genetic testing for patients with SL. This single-center retrospective study characterizes 400 + patients with SL, including IHC results, genetics referrals, and out...
Veiga Pires, Alix
La Maladie d’Alzheimer est une maladie neurodégénérative qui évolue au stade pré-clinique sur plusieurs mois à plusieurs années, précédant le développement des stades prodromique et clinique avec l’apparition de signes de démence. Le chat peut développer une entité apparentée au cours du vieillissement, appelée Syndrome de Dysfonctionnement Cogniti...
Wang, Qiupeng Zhang, Lingna Weng, Shouxiang Zhou, Jingjing Gan, Meifu
Published in
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
9例肠系膜韧带样纤维瘤病患者于2010年1月至2022年5月就诊于温州医科大学附属台州医院，其中男性7例，女性2例，年龄16~59岁；肿瘤位于小肠系膜7例，回盲部系膜1例，横结肠系膜1例；肿瘤最大径3.5~33.0 cm，平均（10.7±8.5）cm，无包膜，界不清，部分病例侵犯肠肌壁组织，切面呈实性，灰白色，质韧。组织病理学检查见梭形的纤维母细胞及肌纤维母细胞平行状、束状或交错排列，埋于大量细胞外胶原内，细胞形态较一致，无明显异型性，核分裂象少见。免疫组织化学检测结果显示，9例患者的肿瘤细胞波形蛋白、β联蛋白均阳性，5例患者α-平滑肌肌动蛋白阳性，Ki-67阳性指数为1%~10%，广谱细胞角蛋白、S-100蛋白、信号转导及转录激活蛋白6、CD117、DOG1、CD34、结蛋白和间变性淋巴瘤...
Guéganou, Florian
Les carcinomes nasaux sont la deuxième tumeur nasale la plus représentée chez le chat derrière les lymphomes nasaux, avec une majorité d'adénocarcinomes. La prise en charge actuellement recommandée est la radiothérapie externe, dont les études montrent une efficacité satisfaisante mais qui reste un traitement peu ciblé aux cellules tumorales, lourd...
Peleman, Cédric De Vos, Winnok H Pintelon, Isabel Driessen, Ann Van Eyck, Annelies Van Steenkiste, Christophe Vonghia, Luisa De Man, Joris De Winter, Benedicte Y Vanden Berghe, Tom
...
Published in
Virchows Archiv : an international journal of pathology
Immunohistochemical stains (IHC) reveal differences between liver lobule zones in health and disease, including nonalcoholic fatty liver disease (NAFLD). However, such differences are difficult to accurately quantify. In NAFLD, the presence of lipid vacuoles from macrovesicular steatosis further hampers interpretation by pathologists. To resolve th...
Tripathi, Kiran Maurya, Niharika Goel, Apul Singhai, Atin Garg, Minal
Published in
Molecular and cellular biochemistry
Mutation or overexpression renders pan-RAS (rat sarcoma) proteins insensitive to inactivation. Activated pan-RAS communicates signal from the cell surface receptor to activate RAS-MAPK/ERK (RAS-mitogen-activated protein kinases/extracellular signal regulated kinases) signaling and orchestrates epithelial-to-mesenchymal transition-activating transcr...
