Aboulhoda, Basma Emad Othman, Doaa Abdullah Rashed, Laila A Alghamdi, Mansour A E Esawy, Abd El Wakeel
Published in
Heliyon
The present study has been designed to detect the dose-dependent effect of iron oxide nanoparticles (IONPs) on the liver and kidney of rats by evaluating three different doses 30, 300, 1000 mg/kg/day IONPs for 28 days. Forty rats were divided into four groups; I (control), II (low dose), III (medium dose) and IV (high dose). There also was a statis...
Clelland, Elle Rothschild, Harriet Patterson, Anne Molina-Vega, Julissa Kaur, Mandeep Symmans, W Schwartz, Christopher Chien, A Benz, Christopher Mukhtar, Rita
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PURPOSE: Recent guidelines defined a new reporting category of ER-low-positive breast cancer based on immunohistochemistry (IHC). While low positivity of either hormone receptor is uncommon in invasive lobular carcinoma (ILC), we sought to investigate whether relatively low hormone receptor positivity was associated with tumor characteristics and p...
Tomlinson, Joanna C L Zwirner, Johann Oorschot, Dorothy E Morawski, Markus Ondruschka, Benjamin Zhang, Ming Hammer, Niels
Published in
Osteoarthritis and cartilage
Capsular repair aims to minimize damage to the hip joint capsular complex (HJCC) and subsequent dislocation risk following total hip arthroplasty (THA). Numerous explanations for its success have been advocated, including neuromuscular feedback loops originating from within the intact HJCC. This research investigates the hypothesis that the HJCC co...
Coulibaly, Zana Ismael Gumus, Nejla Demetter, Pieter
Published in
Annales de pathologie
Peritoneal inclusion cyst is a rare benign tumor. It usually affects women of reproductive age. Its etiology is poorly understood; a history of endometriosis, pelvic inflammatory disease and pelvic surgery are sometimes implicated in its occurrence. Its diagnosis is difficult with complex management. We report the case of a 29-year-old woman presen...
Nimisha, Saluja, Sundeep Singh Sharma, Abhay Kumar Nekarakanti, Phani Kumar Apurva, Kumar, Arun Sattar, Real Sumayya Abdul Anjum, Hasib Batra, Vineeta Vijay Husain, Syed Akhtar
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Published in
Molecular and cellular biochemistry
The function of ABC transporters in the body is manifold; such as maintenance of homeostasis, effect on multi-drug resistance and their role in tumor initiation & progression. Evidence pointing towards the direct or indirect role of ABC transporter genes in particular; ABCB1 and ABCG2 in cancer genesis is increasing. However, their role in gallblad...
Saleh, Jasmine S Subtil, Antonio Hristov, Alexandra C
Published in
Human pathology
Cutaneous T-cell lymphomas are an heterogeneous group of uncommon lymphoid neoplasms that are challenging to diagnose and require close collaboration between dermatologists, pathologists and hematologists/oncologists. This article reviews the most common cutaneous T-cell lymphomas: mycosis fungoides (both classic and variant forms) as well as its l...
Saleh, Jasmine S Whittington, Carli P Bresler, Scott C Patel, Rajiv M
Published in
Human pathology
Cutaneous vascular tumors constitute a heterogeneous group of entities that share overlapping morphologic and immunohistochemical features, which can be diagnostically challenging for pathologists and dermatopathologists. Our understanding and knowledge of vascular neoplasms have improved over time, resulting in both a refinement of their classific...
Hosler, Gregory A Murphy, Kathleen M
Published in
Human pathology
The diagnosis of melanocytic lesions is aided by ancillary testing, but clinical inspection with the histomorphological assessment on biopsy remains sufficient in most cases. Immunohistochemistry and molecular studies have proven useful for diminishing the pool of histomorphologically borderline lesions, and sequential testing may further improve o...
Abdelkareem, Amr O Iews, Mahmoud S Ait-Allah, Abdou S Rasheed, Salah M Helmy, Yasser A Habte, Ruth Abdelhafez, Faten F Bedaiwy, Mohamed A
Published in
Reproductive sciences (Thousand Oaks, Calif.)
Kisspeptin (KP) is a group of hypothalamic neuropeptides encoded by KISS-1 gene. KP-54, a 54-amino-acid peptide, helps regulate the hypothalamic-pituitary-ovarian axis and plays a potential role in implantation. C57BL/6 J female mice were superovulated via intraperitoneal injection of 5 International Units (IU) pregnant mare serum gonadotrophin (da...
Rather, Tahseen Bilal Parveiz, Ishrat Bhat, Gulzar A Rashid, Gowhar Wani, Rauf A Khan, Ishrat Younas Mudassar, Syed
Published in
Clinical and experimental medicine
Forkhead Box M1 (FOXM1)-a key cell cycle regulator is a member of the Forkhead transcription factor family. It plays a key role in embryogenesis and cell proliferation and has been strongly linked to various solid tumors. We sought to understand the regulation of FOXM1 in colorectal cancer (CRC), as well as if and to what extent other clinicopathol...
