Covid-19 and Children with Immune Thrombocytopenia: Emerging Issues
Published in Mediterranean Journal of Hematology and Infectious Diseases
Scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia: a case report and review of the literatu...
Published in Journal of Medical Case Reports
BackgroundScrub typhus is an acute infectious zoonotic disease caused by Orientia tsutsugamushi. Multi-organ dysfunction secondary to scrub typhus is hard to diagnose and has a high mortality rate. Only one case of scrub typhus with multi-organ dysfunction syndrome and immune thrombocytopenia has been reported thus far. In this study, we report a s...
Clinical course of primary immune thrombocytopenia with positive antiphospholipid antibodies.
Published in European journal of internal medicine
Iron deficiency, an unusual cause of thrombocytopenia: results from a multicenter retrospective case-controlled study.
...Published in Annals of hematology
Iron deficiency anemia (IDA) is often associated with mild to moderate thrombocytosis, and iron deficiency-associated thrombocytopenia (IDAT) is much more uncommon and often misdiagnosed as immune thrombocytopenia (ITP). To better describe the features of IDAT, we conducted a retrospective multicenter case-control study. We identified 10 patients (...
Wilson disease associated with immune thrombocytopenia: A case report and review of the literature
Published in World Journal of Clinical Cases
BACKGROUND Wilson disease (WD) is a genetic disorder of hepatic copper excretion, leading to copper accumulation in various tissues. The manifestations are quite variable, and hemolytic anemia is the most common hematological presentation. WD associated with thrombocytopenia is very rare. CASE SUMMARY We report the case of an 11-year-old Chinese gi...
The prediction value of Treg cell subtype alterations for glucocorticoid treatment in newly diagnosed primary immune thr...
...Published in Thrombosis research
Primary immune thrombocytopenia (ITP) is an autoimmune heterogeneous disorder of which Treg cells are numerically or functionally deficient. It is known that human FoxP3+CD4+ T cells were composed of 3 phenotypically and functionally distinct subpopulations (resting Treg, rTreg; activated Treg, aTreg; and non-suppressive Treg, n-sTreg). The current...
Chronic immune thrombocytopenia in Denmark, Sweden and Norway: The Nordic Country Patient Registry for Romiplostim
...Published in EClinicalMedicine
Background Population-based cohorts of immune thrombocytopenia (ITP) are useful for understanding occurrence, clinical characteristics and long-term clinical course. This paper describes the content of the Nordic Country Patient Registry for Romiplostim (NCPRR) and provides prevalence and incidence estimates of chronic ITP (cITP). Methods The NCPRR...
[Treatment of ITP and AIHA in CVID: A systematic literature review].
Published in La Revue de medecine interne
Ten to 15% of common variable immunodeficiencies (CVID) develop auto-immune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP). Treatment is based on immunosuppressants, which produce blocking effects in the CVID. Our objective was to assess their risk-benefit ratio in these immunocompromised patients. We identified 17 articles detailing the...
Thalidomide induce response in patients with corticosteroid-resistant or relapsed ITP by upregulating Neuropilin-1 expre...
...Published in International immunopharmacology
Immune thrombocytopenia (ITP) is an immune-mediated acquired autoimmune hemorrhagic disease. About one-third of patients are unresponsive to first-line therapies. Thalidomide (THD) as an immunomodulatory agent is now used to treat several autoimmune disorders. Therefore, we assessed the safety and efficacy of THD in corticosteroid-resistant or rela...
Immune Cytopenias after Ex Vivo CD34+-Selected Allogeneic Hematopoietic Cell Transplantation.
...Published in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Immune-mediated cytopenias (ICs), such as immune thrombocytopenia and immune hemolytic anemia, are among the adverse events after allogeneic hematopoietic cell transplantation (allo-HCT). Previous reports suggest that in vivo T cell depletion may increase the incidence of IC after allo-HCT. We evaluated whether a strategy that reduces functional do...
