Salido, Marta Solé, Francesc Tusquets, Ignasi Corominas, Josep M. Espinet, Blanca Mariñoso, MaLluïsa Baró, Teresa Vela, MaCarmen Fabregat, Xavier Serrano, Sergi
...
Published in
Revista de Oncología
The HER2/neu protooncogene is expressed in the breast, ovarian, gastric and prostatic tumors. Studies done in a number of laboratories have demostrated that 25%–30% of breast cancer contain overexpression of HER2/neu gene. A comparative analysis of the amplification and overexpression of HER2/neu using fluorescencein situ hybridization (FISH) and i...
Mhawech, P Dulguerov, P Tschanz, E Verdan, C Ares, C Allal, A S
Published in
British journal of cancer
CD9 is a transmembrane protein that has been implicated in cell adhesion, motility and proliferation, and numerous studies have demonstrated the prognostic value of its expression in different solid tumours. The purpose of this study is to determine the predictive value of CD9 in squamous cell carcinoma (SCC) of the head and neck. A total of 153 ca...
Lezmi, Stephane
Dans le but de caractériser chez les ovins l'agent de l'encéphalopathie spongiforme bovine (ESB) responsable du variant de la maladie de Creutzfeldt-Jakob chez l'homme, trois brebis de génotype sensible (2-ARQ/ARQ) ou résistant (1-ARR/ARR) à la tremblante ont été infectées par un cas d'ESB français. La recherche des sites d'accumulation de la proté...
Katz, Eleonora Elgoyhen, Ana Belén Gómez-Casati, María E Knipper, Marlies Vetter, Douglas E Fuchs, Paul A Glowatzki, Elisabeth
Published in
The Journal of neuroscience : the official journal of the Society for Neuroscience
In the mature cochlea, inner hair cells (IHCs) transduce acoustic signals into receptor potentials, communicating to the brain by synaptic contacts with afferent fibers. Before the onset of hearing, a transient efferent innervation is found on IHCs, mediated by a nicotinic cholinergic receptor that may contain both alpha9 and alpha10 subunits. Calc...
Kariola, Reetta Abdel-Rahman, Wael M. Ollikainen, Miina Butzow, Ralf Peltomäki, Päivi Nyström, Minna
Published in
Familial Cancer
Objective: The adenomatous polyposis coli (APC) and β-catenin (CTNNB1) genes are the two major components of the Wnt signaling pathway that has been shown to play an important role in the formation of certain cancers. The overactivation of the pathway, which results in abnormal accumulation of β-catenin protein in nuclei, contributes to most colore...
Dinesh, Kada Peela Bheeman Devaraj, Halagowder Murugan, Vadivel Rajaraman, Ramamurthy Niranjali, Sivasidhambaram
Published in
Molecular and Cellular Biochemistry
BRCA1 is a tumour suppressor gene (TSG), which predisposes cancer to both breast and ovary. The primary objective of the present study is to ascertain the involvement of BRCA1 gene in the pathogenesis of sporadic breast cancer women in Chennai (South India) by analysing its protein expression by immunohistochemistry (IHC) and loss of heterozygosity...
Schönberg, Sharon
Today, the construction of tissue microarrays in order to investigate the expression of proteins and genes on large case series is an approved and accepted method. The applicability of the tissue microarray technique for analysis of bone marrow biopsies has not been tested before and up to now not been mentioned in literature. The aim of our work w...
Massardo, Felipe
Desenvolvimento de um projeto IHC para a ferramenta UseMonitor (desenvolvida pelo prof. Walter Cybis) seguindo uma abordagem de projeto.
Kassab, M. Abd-Elmaksoud, Ahmed Ali, Mona A.
Published in
Journal of Molecular Histology
In the last few decades, several growth factors were identified in the testis of various mammalian species. Growth factors are shown to promote cell proliferation, regulate tissue differentiation, and modulate organogenesis. In the present investigation we have studied the localization of EGF and EGFR in the adult bovine testis by means of immunohi...
Dlugaiczyk, Julia Singer, Wibke Schick, Bernhard Iro, Heinrich Becker, Kristina Becker, Cord-Michael Zimmermann, Ulrike Rohbock, Karin Knipper, Marlies
Published in
Histochemistry and Cell Biology
The cochlear efferent feedback system exerts direct impact on cochlear nerve activity and balances interaural sensitivity. So far, acetylcholine, GABA and dopamine are known to be transmitters of the inhibitory efferent system. Despite the wealth of information about glycinergic neurotransmission in the central auditory system, the inhibitory glyci...
