Increasing lysergic acid levels for ergot alkaloid biosynthesis: Directing catalysis via the F-G loop of Clavine oxidase...
10.3389/fmicb.2023.1150937 / FRONTIERS IN MICROBIOLOGY / 14
Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD
Chronic kidney disease (CKD) is prevalent in 10% of world’s adult population. The role of protein glycosylation in causal mechanisms of CKD progression is largely unknown. The aim of this study was to identify urinary O-linked glycopeptides in association to CKD for better characterization of CKD molecular manifestations. Urine samples from eight C...
Improving aging identifiability of lithium-ion batteries using deep reinforcement learning
As lithium-ion batteries age, the lithium inventory and active materials are gradually lost, limiting their lifespan. The stoichiometric range, which refers to the operable range of the amount of lithium in the electrode, has been considered a representative and comprehensive indicator for predicting the aging process. For the efficient and safe us...
ARSK1 activates TORC1 signaling to adjust growth to phosphate availability in Arabidopsis
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Nutrient sensing and signaling are essential for adjusting growth and development to available resources. Deprivation of the essential mineral phosphorus (P) inhibits root growth.1 The molecular processes that sense P limitation to trigger early root growth inhibition are not known yet. Target of rapamycin (TOR) kinase is a central regulatory hub i...
Meshfree Digital Image Correlation Using Element Free Galerkin Method: Theory, Algorithm and Validation
status: published
Statistical characterization of rainfall fields based upon a 12-year high-resolution radar archive of Belgium
status: published
First-in-Human Study of INCB062079, a Fibroblast Growth Factor Receptor 4 Inhibitor, in Patients with Advanced Solid Tum...
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INTRODUCTION: Fibroblast growth factor receptor (FGFR)-4/FGF19 pathway dysregulation is implicated in hepatobiliary and other solid tumors. INCB062079, an oral, selective, FGFR4 inhibitor, inhibits growth in FGF19/FGFR4-driven liver cancer models. METHODS: This was a two-part, phase I study (NCT03144661) in previously treated patients with advanced...
Mycorrhizal diversity and community composition in co-occurring Cypripedium species
Orchids commonly rely on mycorrhizal fungi to obtain the necessary resources for seed germination and growth. Whereas most photosynthetic orchids typically associate with so-called rhizoctonia fungi to complete their life cycle, there is increasing evidence that other fungi may be involved as well and that the mycorrhizal communities associated wit...
Charting the Lipopeptidome of Nonpathogenic Pseudomonas
A major source of pseudomonad-specialized metabolites is the nonribosomal peptide synthetases (NRPSs) assembling siderophores and lipopeptides. Cyclic lipopeptides (CLPs) of the Mycin and Peptin families are frequently associated with, but not restricted to, phytopathogenic species. We conducted an in silico analysis of the NRPSs encoded by lipopep...
Bacillus lipopeptide-mediated biocontrol of peanut stem rot caused by Athelia rolfsii
status: published
