Qanbari, Saber Gianola, Daniel Hayes, Ben Schenkel, Flavio Miller, Steve Moore, Stephen Thaller, Georg Simianer, Henner
Published in
BMC Genomics
Background'Selection signatures' delimit regions of the genome that are, or have been, functionally important and have therefore been under either natural or artificial selection. In this study, two different and complementary methods--integrated Haplotype Homozygosity Score (|iHS|) and population differentiation index (FST)--were applied to identi...
Smaragdov, M. G.
Published in
Russian Journal of Genetics
The substitution of lysine for alanine (K232A) in the acyl-CoA:diacylglycerol acyltransferase, which is encoded by the DGAT1 gene, was tested for the significance for breeding evaluation of bulls of the holsteinized Black-and-White breed. The breeding value was estimated by the DYDC (daughter yield deviation to contemporaries) method with modificat...
Cánovas, Angela Rincon, Gonzalo Islas-Trejo, Alma Wickramasinghe, Saumya Medrano, Juan F.
Published in
Mammalian Genome
High-throughput sequencing of RNA (RNA-Seq) was developed primarily to analyze global gene expression in different tissues. However, it also is an efficient way to discover coding SNPs. The objective of this study was to perform a SNP discovery analysis in the milk transcriptome using RNA-Seq. Seven milk samples from Holstein cows were analyzed by ...
Meydan, Hasan Yildiz, Mehmet A Agerholm, Jørgen S
Published in
Acta Veterinaria Scandinavica
BackgroundBovine leukocyte adhesion deficiency (BLAD), deficiency of uridine monophosphate synthase (DUMPS), complex vertebral malformation (CVM), bovine citrullinaemia (BC) and factor XI deficiency (FXID) are autosomal recessive hereditary disorders, which have had significant economic impact on dairy cattle breeding worldwide. In this study, 350 ...
Santín, Mónica Fayer, Ronald
Published in
Parasitology Research
Feces from each of 30 Holstein cattle on a Maryland dairy farm were examined at weekly, bimonthly, and then monthly intervals from 1 week to 24 months of age for the presence of Enterocytozoon bieneusi. DNA was extracted from spores cleaned of fecal debris, and a two-step nested PCR protocol was used to amplify a fragment of the internal transcribe...
Smaragdov, M. G.
Published in
Russian Journal of Genetics
Selection using single nucleotide polymorphism (SNP) markers scattered throughout the genome or genomic selection (GS) is considered. This approach permits simultaneous selection of most quantitative trait loci (QTLs) determining the selected trait. According to expert assessment, GS makes it possible to save 92% of the funds spent on traditional s...
Meydan, Hasan Yildiz, Mehmet A Özdil, Fulya Gedik, Yasemin Özbeyaz, Ceyhan
Published in
Acta Veterinaria Scandinavica
BackgroundFactor XI (FXI) is a plasma protein that participates in the formation of blood clots. Factor XI deficiency is autosomal recessive hereditary disorder that may be associated with excess bleeding in Holstein cattle.MethodsIn this study, 225 Holstein cows reared in Turkey were screened in order to identify FXI genotypes. DNA extractions wer...
Agerholm, Jørgen S
Published in
Acta Veterinaria Scandinavica
Hoashi, Shogo Ashida, Nobuhisa Ohsaki, Hideki Utsugi, Takeshi Sasazaki, Shinji Taniguchi, Masaaki Oyama, Kenji Mukai, Fumio Mannen, Hideyuki
Published in
Mammalian Genome
To investigate genetic factors that affect fatty acid composition in beef carcass, we previously investigated genetic profiles of stearoyl-CoA desaturase (SCD) and their effect on fatty acid composition in fat tissue of cattle. It has been known that sterol regulatory element binding protein (SREBP) is a transcription factor that regulates gene exp...
Nassiry, M. R. Eftekhar Shahroodi, F. Mosafer, J. Mohammadi, A. Manshad, E. Ghazanfari, S. Mohammad Abadi, M. R. Sulimova, G. E.
Published in
Russian Journal of Genetics
The bovine lymphocyte antigen (BoLA-DRB3) gene encodes cell surface glycoproteins that initiate immune response by presenting processed antigenic peptides to CD4 T helper cells. DRB3 is the most polymorphic bovine MHC class II gene which encodes the peptide-binding groove. DRB3 gene has been extensively evaluated as a candidate marker for associati...
