Kubo, Hidemasa Murayama, Yasutoshi Ogawa, Soichiro Matsumoto, Tatsuya Yubakami, Masayuki Ohashi, Takuma Kubota, Takeshi Okamoto, Kazuma Kamiya, Mako Urano, Yasuteru
...
Published in
Scientific Reports
Diagnosis of peritoneal metastasis in gastric cancer (GC) is essential for determining appropriate therapeutic strategies and avoiding non-essential laparotomy or gastrectomy. Recently, a variety of activatable fluorescence probes that can detect enzyme activities have been developed for cancer imaging. The aim of this study was to identify the key...
Zullo, Angelo Lahner, Edith Hassan, Cesare Annibale, Bruno Esposito, Gianluca
Published in
GE - Portuguese Journal of Gastroenterology
Introduction: Since screening programs for gastric cancer are not applicable in Western countries, identification and follow-up of gastric precancerous lesions, such as extensive intestinal metaplasia (IM), are worthwhile to increase the diagnosis of cancer at an early stage. We investigated whether an optimal age threshold to detect extensive IM i...
Zurlo, Ina Valeria Schino, Mattia Strippoli, Antonia Calegari, Maria Alessandra Cocomazzi, Alessandra Cassano, Alessandra Pozzo, Carmelo Di Salvatore, Mariantonietta Ricci, Riccardo Barone, Carlo
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Published in
Cancer Immunology, Immunotherapy
The combination of perioperative chemotherapy plus complete surgical resection is currently accounted as the first-choice strategy in patients with locally advanced Gastric Cancer (LAGC). Nevertheless, the partial response rate makes it necessary to search biological parameters useful to select patients who would benefit most from neoadjuvant chemo...
Fukui, Yasuhiro Kubo, Naoshi Sakurai, Katsunobu Tamamori, Yutaka Maeda, Kiyoshi Ohira, Masaichi
Published in
Surgical Case Reports
BackgroundPort site metastasis (PSM) after curative gastrectomy for gastric cancer and muscular metastasis from gastric cancer are rare manifestations. Similarly, subcutaneous metastasis from gastric cancer is rare, and muscular and subcutaneous metastases are associated with poor prognosis. We report a case of long-term survival in a patient who u...
Yang, Na Wu, Yanhua Jin, Meishan Jia, Zhifang Wang, Yueqi Cao, Donghui Qin, Lili Wang, Xueying Zheng, Min Cao, Xueyuan
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Published in
PeerJ
Microsatellite instability (MSI) and Epstein-Barr virus (EBV)-positive molecular subtypes exhibit complex immune responses in gastric cancer (GC), and PD-L1 has emerged as a prognostic biomarker associated with the cancer immune microenvironment. This study aimed to determine the prognostic value of molecular subtypes and whether the addition of PD...
Xie, Jiebin Pang, Yueshan Li, Xun Wu, Xiaoting
Published in
Journal of Cancer Research and Clinical Oncology
Purpose When only the TNM classification is used to predict survival in gastric cancer (GC) patients, the impact of the degree of lymphadenectomy on the prognosis is neglected. This study aimed to establish a more effective nomogram based on the log odds of negative lymph nodes/T stage ratio (LONT) to predict survival in surgically treated GC patie...
Higashidate, Naruki Fukahori, Suguru Ishii, Shinji Saikusa, Nobuyuki Hashizume, Naoki Koga, Yoshinori Masui, Daisuke Sakamoto, Saki Tsuruhisa, Shiori Nakahara, Hirotomo
...
Published in
Surgical Case Reports
BackgroundApart from Kasai’s procedure, liver transplantation (LTx) has dramatically improved the outcome of children with biliary atresia (BA). However, de novo malignancy has been reported to be one of the major causes of late mortality after LTx among adults. We report a rare case of de novo gastric cancer developing after LTx for BA received du...
Chen, Yurong Zhang, Renchao
Published in
Bioengineered
Chun, Sang Hoon Kim, Eun Young Yoon, Jung-Sook Won, Hye Sung Yim, Kwangil Hwang, Hye Won Hong, Soon Auck Lee, Minho Lee, Su Lim Kim, Sung-Soo
...
Published in
BMC Cancer
BackgroundNoggin and RNA-binding protein for multiple splicing 2 (RBPMS2) are known to regulate the expression of smooth muscle cells, endothelial cells, and osteoblasts. However, the prognostic role of combined Noggin and RBPMS2 expression in resected gastric cancer (GC) is unclear.MethodsA total of 163 patients with GC who underwent gastrectomy w...
Santos, M P Pereira, J N Delabio, R W Smith, M A C Payão, S L M Carneiro, L C Barbosa, M S Rasmussen, L T
Published in
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Helicobacter pylori (H. pylori) induces an intense inflammatory response, mediated by proinflammatory cytokines, including interleukin (IL)-6 and its membrane receptor (IL-6R), which activates important signaling pathways in the development of gastric disease and cancer. We investigated the gene and protein expression of IL-6 and IL-6R and the infl...