Hirota, Yu Arai, Aki Young, Larry J Osako, Yoji Yuri, Kazunari Mitsui, Shinichi
Published in
Hormones and behavior
Social relationships among spouses, family members, and friends are known to affect physical and mental health. In particular, long-lasting bonds between socio-sexual partners have profound effects on cognitive, social, emotional, and physical well-being. We have previously reported that pair bonding in monogamous prairie voles (Microtus ochrogaste...
Miedl, Stephan F Rattel, Julina A Franke, Laila K Blechert, Jens Kronbichler, Martin Spoormaker, Victor I Wilhelm, Frank H
Published in
Biological psychiatry. Cognitive neuroscience and neuroimaging
Deficient extinction learning has been suggested as an important mechanism involved in the etiology of posttraumatic stress disorder. A key feature of posttraumatic stress disorder, reexperiencing the trauma in form of intrusions, may be linked to deficient extinction learning. This link is investigated in a novel, functional magnetic resonance ima...
Ebrahimi, Claudia Gechter, Johanna Lueken, Ulrike Schlagenhauf, Florian Wittchen, Hans-Ulrich Hamm, Alfons O. Ströhle, Andreas
Published in
Neuropsychopharmacology
Matsuzaki, Tadanobu
Kyoto University (京都大学) / 0048 / 新制・課程博士 / 博士(医学) / 甲第22318号 / 医博第4559号 / 新制||医||1041(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 渡邉 大, 教授 林 康紀, 教授 伊佐 正 / 学位規則第4条第1項該当
Han, Yuan Zhang, Yi Kim, Haram Grayson, Viktoriya S. Jovasevic, Vladimir Ren, Wenjie Centeno, Maria V. Guedea, Anita L. Meyer, Mariah A. A. Wu, Yixin
...
Published in
Nature Communications
The neuronal pathway that signals the positive or negative value of memories is not well understood. Here, the authors report that an excitatory projection from the ventral tegmental area to the dorsal hippocampus carries the valence information, contributing, especially in females, to the recurrence of fear and to drug seeking behavior.
Summers, Cliff H Yaeger, Jazmine D W Staton, Clarissa D Arendt, David H Summers, Tangi R
Published in
Brain research
Hypothalmic orexin/hypocretin (Orx) neurons in the lateral and dorsomedial perifornical region (LH-DMH/PeF) innervate broadly throughout the brain, and receive similar inputs. This wide distribution, as well as two Orx peptides (OrxA and OrxB) and two Orx receptors (Orx1 and Orx2) allow for functionally related but distinctive behavioral outcomes, ...
da Silva, Thiago Rodrigues Raymundi, Ana Maria Bertoglio, Leandro José Andreatini, Roberto Stern, Cristina A.
Published in
Scientific Reports
The persistence of newly acquired memories is supported by the activity of PKMζ, an atypical isoform of protein kinase C (PKC). Whether the activity of conventional and atypical PKC isoforms contributes to reactivated memories to persist is still unknown. Similarly, whether memory reactivation is a prerequisite for interventions to be able to chang...
Antov, Martin I. Plog, Elena Bierwirth, Philipp Keil, Andreas Stockhorst, Ursula
Published in
Scientific Reports
Neurons in the visual cortex sharpen their orientation tuning as humans learn aversive contingencies. A stimulus orientation (CS+) that reliably predicts an aversive noise (unconditioned stimulus: US) is selectively enhanced in lower-tier visual cortex, while similar unpaired orientations (CS−) are inhibited. Here, we examine in male volunteers how...
Grégoire, Laurent Greening, Steven G
Published in
Cognition & emotion
While modern theories of emotion emphasize the role of higher-order cognitive processes such as semantics in human emotion, much research into emotional learning has ignored the potential contributions of such processes. This study aimed to determine whether emotional learning affects semantic representations of words independent of perceptual feat...
Merz, Christian Josef Eichholtz, Annika Wolf, Oliver Tobias
Published in
Scientific Reports
When using in-group and out-group faces as conditional stimuli (CS) in fear conditioning designs, extinction learning is selectively impaired for out-group faces. Additionally, stress seems to inhibit extinction retrieval leading to a higher return of fear, which might be especially the case for out-group faces. To test this hypothesis, 51 healthy ...
