Published in Psychopharmacology
RationaleDrug use during adolescence results in a lifelong risk to develop substance-use disorders. Adolescent rats are less reactive to cocaine-associated cues compared with adults; however, the contribution of adolescent-formed, context-drug-associations to elicit relapse-like behavior is underexplored. Although it is known that social isolation ...
Published in Journal of applied mathematics & computing
In this paper, a delayed SIQR epidemic model with vaccination and elimination hybrid strategies is analysed under a white noise perturbation. We prove the existence and the uniqueness of a positive solution. Afterwards, we establish a stochastic threshold R s in order to study the extinction and persistence in mean of the stochastic epidemic system...
Published in Current Nutrition Reports
Purpose of Review Dieting is often blamed for causing food cravings. Such diet-induced cravings may be mediated by physiological (e.g., nutritional deprivation) or psychological (e.g., ironic effects of food thought suppression) mechanisms. However, this notion is often based on cross-sectional findings and, thus, the causal role of food deprivatio...
Published in Advances in Difference Equations
In this paper, we propose and analyze a stochastic SIVS model with saturated incidence and Lévy jumps. We first prove the existence of a global positive solution of the model. Then, with the help of semimartingale convergence theorem, we obtain a stochastic threshold of the model that completely determines the extinction and persistence of the epid...
Published in Behavioural brain research
The T-type calcium channel blocker, Z944, has been used as a pharmacological tool to assess T-type calcium channel function and examined for use as an anti-epileptic. As Z944 affects fear learning and memory in a rodent model of absence epilepsy, it is important to determine the effect of Z944 on learning and memory in a non-disease outbred rodent ...
Published in Biological psychiatry
Postretrieval extinction attenuates the pathological memory associated with psychiatric states such as drug addiction in both humans and rodents. The extinction of a learned response requires gene transcription and protein synthesis after memory retrieval in a time-dependent manner, yet the precise physiological basis after retrieval to allow extin...
Published in Behavioural brain research
Dopamine (DA) in medial prefrontal cortex is crucial in extinction of aversive or appetitive experiences. Although attention has been mostly focused on the infralimbic area of prefrontal cortex, a role of the prelimbic (PL) area has been envisaged pointing to DA transmission in the extinction of drug conditioned behavior. Evidence shows that DA exe...
The comment by Gamisch (2020) draws the attention of users of the R-package RPANDA (Morlon et al. 2016) on situations when properly interpreting the results of linear diversification dependencies requires caution. Here we provide clarifications to help users interpreting their results when using any type of functional diversification dependencies w...
Published in Biological psychiatry
While translational theories link neurodevelopmental changes in threat learning to pathological anxiety, findings from studies in patients inconsistently support these theories. This inconsistency may reflect difficulties in studying large patient samples with wide age ranges using consistent methods. A dearth of imaging data in patients further li...
Published in Invertebrate Neuroscience
Conditioned taste aversion (CTA) in the freshwater pulmonate Lymnaea stagnalis can be formed by presenting ten pairings of sucrose as the conditioned stimulus (CS) and KCl as the unconditioned stimulus (US). The CTA is consolidated to long-term memory (LTM) lasting longer than a month. In the present study, we examined the time course of protein sy...
