Rodbard, David
Published in
Diabetes technology & therapeutics
The ambulatory glucose profile (AGP) and the frequency distribution for glucose by ranges are well established as standard methods for display, analysis, and interpretation of glucose data arising from self-monitoring, continuous glucose monitoring, and automated insulin delivery systems. In this review, we consider several refinements that may fur...
Hauer, Klaus Ullrich, Phoebe Heldmann, Patrick Hummel, Saskia Bauer, Jürgen M. Werner, Christian
Published in
BMC Geriatrics
BackgroundSelf-reported life-space assessment methods so far focus on community-dwelling persons, with a lack of validated assessment methods for institutionalized settings. This study evaluated construct validity, test-retest reliability, sensitivity to change, and feasibility of a new Life-Space Assessment for Institutionalized Settings (LSA-IS) ...
Schafer, Zoe A Vanicek, Natalie
Published in
Gait & posture
Individuals with a lower limb amputation (LLA) have an increased risk of falls and often report lower balance confidence. They must compensate for altered mechanics and prosthetic limitations in order to execute appropriate motor responses to postural perturbations. Personalised exercise could be an effective strategy to enhance balance and reduce ...
Ha, Hyungserk Jung, Eun Jin Koh, Kanghyock
Published in
Economics and human biology
A delayed school start time (DSST), achieved by removing zero period, could change students' other time use during school as well as other forms of human capital accumulation. Using difference-in-differences, we find evidence that a DSST in South Korea reduced the time students spent in gym class without worsening students' health status. Combined ...
Schmitter, Michèle Spijker, Jan Smit, Filip Tendolkar, Indira Derksen, Anne-Marie Oostelbos, Peter Wijnen, Ben F. M. van Doesum, Tessa J. Smits, Jasper A. J. Vrijsen, Janna N.
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Published in
BMC Psychiatry
BackgroundMajor depressive disorder (MDD) is a considerable public health concern. In spite of evidence-based treatments for MDD, many patients do not improve and relapse is common. Therefore, improving treatment outcomes is much needed and adjunct exercise treatment may have great potential. Exercise was shown to be effective as monotherapy for de...
Liao, Wen-Ling Chang, Yu-Hung
Published in
BMC Geriatrics
BackgroundThis study aims to identify the age trajectories of disability in instrumental activities of daily life (IADLs) over 11 years and their correlates, and to estimate disability-free life expectancy for identified trajectory groups in middle-aged and older adults.MethodsWe included 3118 participants aged 50 and over without IADL limitations ...
Leonard, A N Shill, A L Thackray, A E Stensel, D J Bishop, Nicolette C
Published in
European journal of applied physiology
Asprosin, an orexigenic hormone that stimulates hepatic glucose release, is elevated in insulin resistance and associated with obesity. Plasma asprosin concentrations may also be related to female sex hormone levels; higher levels are reported in women with polycystic ovary syndrome (PCOS) but this may be related to peripheral insulin resistance al...
Morales Febles, Raúl Negrín Mena, Natalia Rodríguez-Rodríguez, Ana Elena Díaz Martín, Laura González Rinne, Federico Marrero Miranda, Domingo González Rinne, Ana Álvarez González, Alejandra Pérez Tamajón, Lourdes Acosta Sørensen, Cristian
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Published in
Nephron
Background: Post-transplant diabetes mellitus (PTDM) is a frequent and severe complication after renal transplantation. In fact, PTDM is a risk factor for both infection and cardiovascular diseases. The prevalence and incidence of PTDM have a bimodal evolution: early (up to 3 months) and late PTDM (beyond 12 months). The majority of late PTDM occur...
Bass, Joseph J Nakhuda, Asif Deane, Colleen S Brook, Matthew S Wilkinson, Daniel J Phillips, Bethan E Philp, Andrew Tarum, Janelle Kadi, Fawzi Andersen, Ditte
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Published in
Molecular metabolism
The Vitamin D receptor (VDR) has been positively associated with skeletal muscle mass, function and regeneration. Mechanistic studies have focused on the loss of the receptor, with in vivo whole-body knockout models demonstrating reduced myofibre size and function and impaired muscle development. To understand the mechanistic role upregulation of t...
Dao, Tam Green, Alexander E Kim, Yun A Bae, Sung-Jin Ha, Ki-Tae Gariani, Karim Lee, Mi-Ra Menzies, Keir J Ryu, Dongryeol
Published in
Endocrinology and metabolism (Seoul, Korea)
The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns. Sarcopenia is a condition which is defined by the gradual loss of skeletal muscle mass and function with age. In research and clinical practice, sarcopenia is recognized as a component...