Publication search
with Eurycomanone as keyword
Bhat, Irfan Ahmad Rather, Mohd Ashraf Nazir, Mir Ishfaq Pathakota, Gireesh-Babu Goswami, Mukunda Sundaray, J K Sharma, Rupam
Published in
Theriogenology
Fish like higher animals, have a well-defined mechanism to produce sex steroids that play a critical role in gonadal development and maturation. In this study, we aimed to analyse the expression pattern of 3β-HSD in different tissues, during ontogenetic development and gonadal recrudescence of Clarias batrachus. A full-length cDNA of 1617 bp includ...
Hajjouli, Shéhérazade Chateauvieux, Sébastien Teiten, Marie-Hélène Orlikova, Barbora Schumacher, Marc Dicato, Mario Choo, Chee-Yan Diederich, Marc
Published in
Molecules
Eurycomanone and eurycomanol are two quassinoids from the roots of Eurycoma longifolia Jack. The aim of this study was to assess the bioactivity of these compounds in Jurkat and K562 human leukemia cell models compared to peripheral blood mononuclear cells from healthy donors. Both eurycomanone and eurycomanol inhibited Jurkat and K562 cell viabili...
Pan, Yan Tiong, Kai Hung Abd-Rashid, Badrul Amini Ismail, Zakiah Ismail, Rusli Mak, Joon Wah Ong, Chin Eng
Published in
Journal of Natural Medicines
Eurycomanone, an active constituent isolated from Eurycoma longifolia Jack, was examined for modulatory effects on cytochrome P450 (CYP) isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 using in vitro assays. The IC50 value was determined to assess the potencies of modulation for each CYP isoform. Our results indicated that euryc...
