Amorim, Claudio Luiz Castro Gomes de Oliveira, Joice Mara de Rodrigues, Antenor Furlanetto, Karina Couto Pitta, Fabio
ABSTRACT In this cross-sectional study, we investigated the relationship that levels of vitamin D had with eosinophil counts and IgE levels in 26 children with asthma (6-12 years of age) in the city of Londrina, Brazil. Vitamin D levels were found to correlate significantly, albeit moderately, with age (r = −0.51) and eosinophilia (r = −0.49), alth...
Willems, Mégane Willems, Luc
Fercoq, Frédéric Remion, Estelle Vallarino-Lhermitte, Nathaly Alonso, Joy Raveendran, Lisy Nixon, Colin Le Quesne, John Carlin, Leo M. Martin, Coralie
Published in
Parasites & Vectors
BackgroundPulmonary manifestations are regularly reported in both human and animal filariasis. In human filariasis, the main known lung manifestations are the tropical pulmonary eosinophilia syndrome. Its duration and severity are correlated with the presence of microfilariae. Litomosoides sigmodontis is a filarial parasite residing in the pleural ...
Singh, Meenal Singh, Vivekanand Schurman, Jennifer V Friesen, Craig A
Published in
Digestive diseases and sciences
Chronic gastritis is a common histologic finding in children with functional dyspepsia (FD). While Th17 cells have been implicated in other forms of gastritis, they have not been evaluated in chronic gastritis. The aim of the current study was to assess Th17 cells in children with FD with and without chronic gastritis. Densities were determined for...
Singh, Dave Virchow, Johann Christian Canonica, Giorgio Walter Vele, Andrea Kots, Maxim Georges, George Papi, Alberto
Published in
Respiratory Research
BackgroundA number of single-inhaler triple therapies are being developed for asthma, including the extrafine formulation of beclometasone dipropionate (BDP), formoterol fumarate (FF), and glycopyrronium (G). Given asthma is a heterogenous disease, we investigated whether the clinical response to the addition of the long-acting muscarinic antagonis...
Ari, Selma Can, Veysi Demir, Ömer Furkan Ari, Hasan Ağca, Fahriye Vatansever Melek, Mehmet Çamci, Sencer Dikiş, Özlem Şengören Huysal, Kağan Türk, Tamer
...
Published in
Journal of hematopathology
Despite prophylactic anticoagulant treatments, thrombotic complications may develop in patients with coronavirus disease 2019 (COVID-19). This study aimed to evaluate the factors influencing anti-factor Xa activity in COVID-19 patients receiving low molecular weight heparin (LMWH). We prospectively evaluated 80 COVID-19 patients, diagnosed using po...
Grosicki, Marek Adami, Maristella Micheloni, Cristina Głuch-Lutwin, Monika Siwek, Agata Latacz, Gniewomir Łażewska, Dorota Więcek, Małgorzata Reiner-Link, David Stark, Holger
...
Published in
European journal of pharmacology
Histamine is a pleiotropic biogenic amine, having affinity towards four distinct histamine receptors. The existing pharmacological studies suggest the usefulness of histamine H4 receptor ligands in the treatment of many inflammatory and immunomodulatory diseases, including allergic rhinitis, asthma, atopic dermatitis, colitis or pruritus. Up to dat...
Hamilton, Daniel Lehman, Heather
Published in
Clinical reviews in allergy & immunology
Asthma has been increasingly recognized as being a heterogeneous disease with multiple distinct mechanisms and pathophysiologies. Evidence continues to build regarding the existence of different cell types, environmental exposures, pathogens, and other factors that produce a similar set of symptoms known collectively as asthma. This has led to a mo...
Choudhury, Shelly Baker, Susan
Published in
Clinical reviews in allergy & immunology
Eosinophilic esophagitis (EoE) is a chronic, relapsing inflammatory disease of the esophagus, characterized by the presence of significant esophageal mucosal eosinophilic infiltrates. The clinical presentation of EoE in childhood may include failure to thrive and feeding intolerance. The complication of food impaction is often related to the presen...
Mavissakalian, Matthew Brady, Sean
Published in
Clinical reviews in allergy & immunology
Asthma is a heterogeneous disease, with the immune processes behind the chronic inflammation underlying this disorder differing between the various identified asthma endotypes. In addition to heterogeneity in underlying disease pathophysiology, asthmatics fall across a broad spectrum of disease severity and can vary greatly in their response to con...