Vancomycin is commonly used in outpatient parenteral antimicrobial therapy (OPAT) of Gram-positive infections. Therapeutic drug monitoring and adverse event monitoring pose a challenge. Outcome data of vancomycin in OPAT (vOPAT) are limited. The study aim was to report the safety and efficacy of a structured vOPAT program implemented in the Univers...
Citizens in many countries are now experiencing record-smashing heatwaves that were intensified due to anthropogenic climate change. Whether today’s most impactful heatwaves could have occurred in a pre-industrial climate, traditionally a central focus of attribution research, is fast becoming an obsolete question. The next frontier for attribution...
Published in Acta clinica Belgica
ObjectivesInterdisciplinary bedside rounds is gaining ground as a method to improve patient centredness and involvement, quality of care and team collaboration. An exploratory study was conducted in Flemish hospitals to (1) map and (2) examine the current form of rounds and the extent to which these were bedside, patient and family participatory an...
PURPOSE: Drug-related admissions (DRAs) are an important cause of preventable harm in older adults. Multiple algorithms exist to assess causality of adverse drug reactions, including the Naranjo algorithm and an adjusted version of the Kramer algorithm. The performance of these tools in assessing DRA causality has not been robustly shown. This stud...
OBJECTIVES: In the third report of the European Registry for Patients with Mechanical Circulatory Support of the European Association for Cardio-Thoracic Surgery, outcomes of patients receiving mechanical circulatory support are reviewed in relation to implant era. METHODS: Procedures in adult patients (January 2011-June 2020) were included. Patien...
It remains debated whether pulse pressure is associated with left ventricular traits and adverse outcomes over and beyond mean arterial pressure (MAP) in patients with heart failure (HF) with preserved ejection fraction. We investigated these associations in 3428 patients with HF with preserved ejection fraction (51.5% women; mean age, 68.6 years) ...
The Ruminative Response Scale (RRS) is commonly used to measure people's general tendency to ruminate. In this study, we explored whether only few items from the RRS can be used to capture within-person variation in rumination in intensive longitudinal studies. Such a short RRS version would allow, for example, monitoring the development of ruminat...
The importance of perioperative respiration monitoring is highlighted by high incidences of postoperative respiratory complications unrelated to the original disease. The objectives of this pilot study were to (1) simultaneously acquire respiration rate (RR), tidal volume (TV), minute ventilation (MV), SpO(2) and PetCO(2) from patients in post-anes...
Published in Journal of patient safety
The primary aim was to measure resident safety culture in six nursing homes in northern Belgium (Flanders). In addition, differences in safety culture perceptions between professions were also examined. Finally, results of the present study were compared with the Nursing Home Comparative Database from the Agency for Healthcare Research and Quality ...
The authors examined the contrasting factors behind the distinct increases in hot days (HDs, daytime hot extremes) and warm nights (WNs, nighttime hot extremes) over land in the Northern Hemisphere during the boreal summers (June to August) of 1980?2018. While the occurrence of HDs has increased gradually since 1980, that of WNs increased abruptly ...
