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The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in viv...

Published in Neurobiology of Disease

• Epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro; • Epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro; • DYRK1A levels and activity is increased in CDKL5 deficient neurons;