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Watanabe, Atsushi Naing, Banyar Than Shimada, Takashi
Published in
Current Genetic Medicine Reports
Pharmacogenomics (PGx) involves investigation into the genetic basis of interindividual differences in drug responses, such as efficacy, dose requirements, and adverse events. PGx can be used as a tool for personalizing health care on the basis of individual genetic variations. It may decrease the amount of time needed to identify the most benefici...
Duque-Guimarães, Daniella Ong, Thomas Prates de Almeida-Faria, Juliana Guest, Paul C Ozanne, Susan E
Published in
Advances in experimental medicine and biology
Stable isotope labelling by amino acids in cell culture (SILAC) is a technique that allows proteomic profiling of cells. In this chapter we describe a protocol for the identification and quantification of newly synthesised proteins. The methodology can be applied to any cultured cell system with relevance to schizophrenia, affective disorders and a...
Duque-Guimarães, Daniella Ong, Thomas Prates de Almeida-Faria, Juliana Guest, Paul C Ozanne, Susan E
Stable isotope labelling by amino acids in cell culture (SILAC) is a technique that allows proteomic profiling of cells. In this chapter we describe a protocol for the identification and quantification of newly synthesised proteins. The methodology can be applied to any cultured cell system with relevance to schizophrenia, affective disorders and a...
Tian, Lei Oikonomopoulos, Angelos Liu, Chun Kitani, Tomoya Shrestha, Rajani Chen, Christopher L Ong, Sang-Ging Smeets, Mark Karakikes, Ioannis Sayed, Nazish
...
Published in
Circulation
Wang, Feng Zhu, Lei
Published in
Heliyon
Background Phenotypic plasticity (PP) is a major promoter of tumor metastasis and drug resistance. Nevertheless, the molecular features and clinical significance of phenotypic plasticity in lung squamous cell carcinomas (LSCC) remained largely unexplored. Methods Phenotypic plasticity-related genes (PPRG) and clinical information of LSCC were downl...
Li, Yangyang Guo, Yan Chen, Fengzhi Cui, Yuqing Chen, Xuesong Shi, Guangyue
Published in
Translational Oncology
Background Male breast cancer (MBC) is a rare malignancy with a worse prognosis than female breast cancer (FBC). Current MBC treatment strategies are based on those for FBC. However, molecular differences between MBC and FBC with respect to prognosis and drug responses remain unclear. Methods After controlling for confounding factors with propensit...
