Goldfarb, Shari B Turan, Volkan Bedoschi, Giuliano Taylan, Enes Abdo, Nadia Cigler, Tessa Bang, Heejung Patil, Sujita Dickler, Maura N Oktay, Kutluk H
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Published in
Breast cancer research and treatment
To determine the longitudinal impact of adjuvant chemotherapy and tamoxifen-only treatments on the reproductive potential of women with breast cancer by using a sensitive ovarian reserve marker anti-Mullerian hormone (AMH) as a surrogate. One-hundred-and-forty-two women with a primary diagnosis of breast cancer were prospectively followed with seru...
Coelho, Juliana Chaves Guimarães, Mayra Cristina da Luz Pádua Campos, Cassia Lima de Florido, Carime Farah Silva, Giovanio Vieira da Pierin, Angela Maria Geraldo
Abstract Introduction: Arterial hypertension is a disease that has a high impact on cardiovascular mortality and morbidity; however, it is still insufficiently controlled. Objectives: To assess hypertension control in patients seen at a specialized clinic and to identify associated variables. Method: Cross-sectional study involving the analysis of ...
Abouzari, Mehdi Goshtasbi, Khodayar Chua, Janice T Tan, Donald Sarna, Brooke Saber, Tina Lin, Harrison W Djalilian, Hamid R
Objectives/hypothesisTo examine the hearing outcomes of patients with sudden sensorineural hearing loss (SSNHL) treated with oral and intratympanic (IT) steroid only or a combination of steroid and migraine treatment. Our hypothesis was that adjuvant migraine medications may improve outcomes in SSNHL.MethodsA retrospective chart review at a tertiar...
Ribeiro, José Francisco Figueiredo, Maria do Livramento Fortes Carvalho, André Luís Menezes Sousa Neto, Benedito Pereira de
Objective: to identify the pharmacological activities of bacuri butter (Platonia insignis Mart.). Methods: an integrative review, carried out in the databases of Latin American and Caribbean Literature in Health Sciences, Cumulative Index to Nursing and Allied Health Literature, EMBASE, MEDLINE/PubMed, Web of Science, Cochrane Library and SCOPUS, w...
RODRIGUES, RUY DA SILVA SIQUEIRA, EDUARDO BASTOS DE BRITO, LEANDRO GOMES FAGUNDES, RUDY LENK RIBEIRO, CAIO TANNUS VIANNA
ABSTRACT Objective To describe the daily practice in an emergency service and to provide relevant data for future studies about the treatment of low back pain from the perspective of emergency medicine. Methods Analysis of hospital records and review of medical records. Results 2,434 patients were attended between January 1 and December 31, 2017 wi...
Nicol, Melanie R Joshi, Abhay Rizk, Matthew L Sabato, Philip E Savic, Radojka M Wesche, David Zheng, Jenny H Cook, Jack
Chloroquine and hydroxychloroquine are quinoline derivatives used to treat malaria. To date, these medications are not approved for the treatment of viral infections, and there are no well-controlled, prospective, randomized clinical studies or evidence to support their use in patients with coronavirus disease 2019 (COVID-19). Nevertheless, chloroq...
Shaw, Jeremy J P Boyer, Timothy L Venner, Emily Beck, Patrick J Slamowitz, Tristen Caste, Tara Hickman, Alexandra Raymond, Michael H Costa-Pinheiro, Pedro Jameson, Mark J
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Published in
Molecular cancer therapeutics
Therapies for head and neck squamous cell carcinoma (HNSCC) are, at best, moderately effective, underscoring the need for new therapeutic strategies. Ceramide treatment leads to cell death as a consequence of mitochondrial damage by generating oxidative stress and causing mitochondrial permeability. However, HNSCC cells are able to resist cell deat...
Nandini, D B Rao, Roopa S Hosmani, Jagadish Khan, Samar Patil, Shankargouda Awan, Kamran Habib
Published in
Disease-a-month : DM
An estimated 4% of all cancers are of the oral cavity or oropharyngeal. Presently, management of the oral cancers mainly includes surgery, radiotherapy, and chemotherapy either alone or in combination depending on the individual case. Each of these techniques has their advantages and disadvantages. Surgery demands removal of cancerous tissue causin...
Kidd, Vasco Lowe, Andrew Luu, Brent Kayingo, Gerald
The management of patients with acute and chronic nonmalignant pain represents a real challenge for practicing clinicians. The chronic use of opioids now carries an “addiction-related” stigma and concerns about efficacy and safety of opiates have been called into question. Overprescribing of opioids and opiates by clinicians in various disciplines ...
Nagai, Kazumasa Kitamura, Katsuya Hirai, Yuji Nutahara, Daisuke Nakamura, Hironori Taira, Junichi Matsue, Yubu Abe, Masakazu Kikuchi, Miho Itoi, Takao
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Published in
Internal medicine (Tokyo, Japan)
Cancer patients are regarded as highly vulnerable to SARS-CoV-2. However, little is known regarding how cancer treatments should be restarted for cancer patients after COVID-19. We herein report a pancreatic cancer case in which chemotherapy was able to be reinstituted after COVID-19. The patient was a 67-year-old man diagnosed with pancreatic canc...
