Experimental verification of a diagnostic model for reciprocating chillers
Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering / 211 / 4 / 259-265 / PMEEE
Non-invasive models for predicting histology in patients with chronic hepatitis B
10.1111/j.1478-3231.2006.01287.x / Liver International / 26 / 6 / 666-672
Non-invasive models for predicting histology in patients with chronic hepatitis B
Liver International / 26 / 6 / 666-672 / LIINC
Predictive models of autism spectrum disorder based on brain regional cortical thickness.
Published in NeuroImage
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a wide phenotypic range, often affecting personality and communication. Previous voxel-based morphometry (VBM) studies of ASD have identified both gray- and white-matter volume changes. However, the cerebral cortex is a 2-D sheet with a highly folded and curved geometry, which VBM...
Single Nucleotide Polymorphisms Predict Symptom Severity of Autism Spectrum Disorder
Published in Journal of Autism and Developmental Disorders
Autism is widely believed to be a heterogeneous disorder; diagnosis is currently based solely on clinical criteria, although genetic, as well as environmental, influences are thought to be prominent factors in the etiology of most forms of autism. Our goal is to determine whether a predictive model based on single-nucleotide polymorphisms (SNPs) ca...
Discovery of serum protein biomarkers in rheumatoid arthritis using MALDI-TOF-MS combined with magnetic beads
Published in Clinical and Experimental Medicine
The aim of this study was to discover potential biomarkers for rheumatoid arthritis (RA) using Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry combined with magnetic beads. Proteomic fingerprint technology combining magnetic beads with MALDI-TOF-MS was used to profile and compare the proteomes in serum samples from 60 p...
Detection of serum tumor markers in multiple myeloma using the CLINPROT system
Published in International Journal of Hematology
The discovery of biomarkers unique to multiple myeloma (MM) is of great importance to clinical practice. This study was designed to identify serum tumor marker candidates of MM in the mass range of 700–10000 Da. Serum samples from 48 MM patients and 74 healthy controls were collected and classified into a training dataset (MM/controls: 26/26) and a...
A Clinical Analysis of 293 FUO Patients, A Diagnostic Model Discriminating infectious Diseases from Non-infectious Disea...
Published in Infection International
Objective A diagnostic model was established to discriminate infectious diseases from non-infectious diseases. Methods The clinical data of patients with fever of unknown origin (FUO) hospitalized in Xiangya Hospital Central South University, from January, 2006 to April, 2011 were retrospectively analyzed. Patients enrolled were divided into two gr...
Evaluation of a Diagnostic Model of an Air Velocity Field: The Must Wind Tunnel Case
Published in Environmental Modeling & Assessment
The paper presents the application of a diagnostic model of an air velocity field in complex geometric settings. A variational algorithm is used to satisfy the criterion of mass balance. The formulated elliptic-type equation is solved with conformal mapping and the finite difference method for a non-equidistant discretisation net. A series of trans...
Validation of N-glycan markers that improve the performance of CA19-9 in pancreatic cancer
Published in Clinical and Experimental Medicine
Pancreatic cancer (PC) has a high mortality rate because it is usually diagnosed late. Glycosylation of proteins is known to change in tumor cells during the development of PC. The objectives of this study were to identify and validate the diagnostic value of novel biomarkers based on N-glycomic profiling for PC. In total, 217 individuals including...
